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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS16
All Species:
22.73
Human Site:
Y134
Identified Species:
50
UniProt:
Q8N2M8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2M8
NP_008987.2
674
77161
Y134
I
S
E
E
Q
C
L
Y
Q
I
Y
I
D
E
L
Chimpanzee
Pan troglodytes
XP_001163165
677
77527
Y134
I
S
E
E
Q
C
L
Y
Q
I
Y
I
D
E
L
Rhesus Macaque
Macaca mulatta
XP_001110131
676
77338
Y134
I
S
E
E
Q
C
L
Y
Q
I
Y
I
D
E
L
Dog
Lupus familis
XP_852504
475
53399
K32
R
R
R
E
Y
Y
E
K
I
K
K
D
P
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFC7
668
76806
Y134
I
S
E
E
Q
C
L
Y
Q
I
Y
I
D
E
L
Rat
Rattus norvegicus
Q5HZB6
668
76788
Y134
I
S
E
E
Q
C
L
Y
Q
I
Y
I
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMJ9
888
100785
Q133
L
K
K
E
E
I
K
Q
R
Q
I
E
Q
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001037794
642
74464
Y135
I
S
E
E
Q
C
L
Y
Q
I
Y
V
D
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996288
715
79992
H136
V
S
E
D
K
F
L
H
Q
L
Y
L
E
E
Q
Honey Bee
Apis mellifera
XP_001121363
1575
184935
H132
V
T
E
E
K
F
L
H
Q
I
H
L
E
E
Q
Nematode Worm
Caenorhab. elegans
NP_506124
672
79482
K137
V
S
E
K
H
Y
L
K
K
I
A
D
R
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.2
60
N.A.
94.9
95.2
N.A.
N.A.
20.7
N.A.
70.6
N.A.
35.5
23.1
30.1
N.A.
Protein Similarity:
100
98.9
99.4
63.2
N.A.
96.1
96.2
N.A.
N.A.
35.4
N.A.
78
N.A.
50.3
30.7
46.5
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
13.3
N.A.
93.3
N.A.
40
40
33.3
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
40
N.A.
100
N.A.
86.6
86.6
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
19
55
0
0
% D
% Glu:
0
0
82
82
10
0
10
0
0
0
0
10
19
91
0
% E
% Phe:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
19
0
0
10
0
0
0
0
% H
% Ile:
55
0
0
0
0
10
0
0
10
73
10
46
0
0
0
% I
% Lys:
0
10
10
10
19
0
10
19
10
10
10
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
82
0
0
10
0
19
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
55
0
0
10
73
10
0
0
10
0
28
% Q
% Arg:
10
10
10
0
0
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
28
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
19
0
55
0
0
64
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _