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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL34
All Species:
15.76
Human Site:
Y559
Identified Species:
43.33
UniProt:
Q8N239
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N239
NP_695002.1
644
70612
Y559
T
R
L
R
P
L
P
Y
D
R
F
C
Y
G
L
Chimpanzee
Pan troglodytes
XP_529234
594
65141
Y509
T
R
L
R
P
L
P
Y
D
R
F
C
Y
G
L
Rhesus Macaque
Macaca mulatta
XP_001086668
643
70516
Y558
T
R
L
R
P
L
P
Y
D
R
F
C
Y
G
L
Dog
Lupus familis
XP_548889
1038
112221
Y950
T
R
L
R
P
L
P
Y
D
R
F
C
Y
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPT1
617
69381
R533
T
P
I
A
A
M
L
R
G
Q
S
D
V
G
V
Rat
Rattus norvegicus
Q66HD2
613
69917
Q532
T
R
V
A
P
L
L
Q
A
N
S
E
S
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLD3
629
70952
R549
T
P
I
A
A
M
L
R
G
Q
S
D
V
G
V
Frog
Xenopus laevis
Q6DFF7
589
66062
A526
T
R
I
G
D
M
T
A
K
R
M
S
C
H
A
Zebra Danio
Brachydanio rerio
Q503R4
605
68451
Y534
T
M
I
A
P
L
R
Y
A
S
S
E
A
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.6
96.4
55.1
N.A.
30.7
30.7
N.A.
N.A.
31.2
22.2
30.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.7
97.9
57.6
N.A.
48.2
48.1
N.A.
N.A.
48.5
39.5
45.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
13.3
33.3
N.A.
N.A.
13.3
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
46.6
N.A.
N.A.
40
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
23
0
0
12
23
0
0
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
45
12
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
45
0
0
23
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
23
0
0
0
0
89
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
45
0
0
67
34
0
0
0
0
0
0
0
56
% L
% Met:
0
12
0
0
0
34
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
23
0
0
67
0
45
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
12
0
23
0
0
0
0
0
% Q
% Arg:
0
67
0
45
0
0
12
23
0
56
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
12
45
12
12
0
0
% S
% Thr:
100
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
0
23
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
45
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _