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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR16
All Species:
31.82
Human Site:
T591
Identified Species:
63.64
UniProt:
Q8N1V2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1V2
NP_001074025.1
620
68298
T591
V
G
H
S
G
N
I
T
R
I
R
I
S
P
G
Chimpanzee
Pan troglodytes
XP_511843
1810
198756
T597
V
G
H
S
G
N
I
T
R
I
R
I
S
P
G
Rhesus Macaque
Macaca mulatta
XP_001118238
1783
194926
T591
V
G
H
S
G
N
I
T
R
I
R
I
S
P
G
Dog
Lupus familis
XP_536639
649
71139
T620
V
G
H
S
G
N
I
T
R
I
R
I
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5F201
620
68222
M591
V
G
H
S
G
N
I
M
A
M
R
I
S
P
G
Rat
Rattus norvegicus
NP_001094438
620
68282
M591
V
G
H
S
G
N
I
M
G
I
R
I
S
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515117
621
68030
T592
V
G
H
S
G
C
I
T
C
L
K
I
S
P
G
Chicken
Gallus gallus
XP_415591
619
67906
T590
V
G
H
S
G
N
I
T
R
L
K
I
C
P
G
Frog
Xenopus laevis
NP_001089460
617
68025
T587
I
G
H
S
G
N
I
T
R
L
K
I
C
P
I
Zebra Danio
Brachydanio rerio
NP_001018475
617
67903
T588
I
G
H
S
G
S
I
T
N
V
R
I
C
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624617
654
73164
T619
L
A
H
A
A
A
V
T
R
C
V
F
A
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787783
635
70344
K604
V
G
H
C
S
E
I
K
R
L
R
I
C
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
33.8
88.4
N.A.
90.8
90.6
N.A.
77.6
70
68.8
63.3
N.A.
N.A.
39.2
N.A.
54.3
Protein Similarity:
100
32.8
34.4
92.9
N.A.
95.9
95.9
N.A.
89.5
84.1
84
82
N.A.
N.A.
60.5
N.A.
71.1
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
73.3
80
66.6
60
N.A.
N.A.
26.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
93.3
86.6
80
N.A.
N.A.
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
9
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
9
0
9
0
0
9
9
0
0
34
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
92
0
0
84
0
0
0
9
0
0
0
0
0
67
% G
% His:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
17
0
0
0
0
0
92
0
0
42
0
92
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
25
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
17
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
67
0
0
9
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
67
0
67
0
0
0
0
% R
% Ser:
0
0
0
84
9
9
0
0
0
0
0
0
59
0
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% T
% Val:
75
0
0
0
0
0
9
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _