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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK4
All Species:
20.3
Human Site:
S258
Identified Species:
74.44
UniProt:
Q8N1I0
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1I0
NP_055520.3
1966
225148
S258
D
K
P
E
R
H
C
S
L
F
V
D
L
G
S
Chimpanzee
Pan troglodytes
XP_519315
1970
225552
S258
D
K
P
E
R
H
C
S
L
F
V
D
L
G
S
Rhesus Macaque
Macaca mulatta
XP_001092040
1061
121740
Dog
Lupus familis
XP_539524
1991
227485
S276
D
K
P
E
R
H
C
S
L
F
V
D
L
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P59764
1978
226531
S258
D
K
P
E
R
H
C
S
L
F
V
D
L
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733258
2171
245836
T277
E
R
L
H
S
N
C
T
V
F
T
D
L
G
A
Honey Bee
Apis mellifera
XP_001121716
1928
220359
T290
E
K
I
H
S
N
C
T
I
F
T
D
L
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
53.5
95.4
N.A.
97.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36
40.4
N.A.
N.A.
Protein Similarity:
100
99.8
53.5
96.5
N.A.
98.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
55.7
60.3
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
40
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% C
% Asp:
58
0
0
0
0
0
0
0
0
0
0
86
0
0
0
% D
% Glu:
29
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
86
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
0
% G
% His:
0
0
0
29
0
58
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
15
0
0
0
0
0
0
% I
% Lys:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
0
0
0
58
0
0
0
86
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
29
0
0
0
0
0
0
0
0
15
% N
% Pro:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
58
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
29
0
0
58
0
0
0
0
0
0
58
% S
% Thr:
0
0
0
0
0
0
0
29
0
0
29
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
15
0
58
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _