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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXL14 All Species: 5.15
Human Site: S314 Identified Species: 10.3
UniProt: Q8N1E6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N1E6 NP_689654.1 418 45886 S314 L K S L S L C S C H I S D D G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117874 404 44252 G303 S L A Y I A Q G L D G L K S L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BID8 400 43846 Y299 V G D Q S L A Y I A Q G L D G
Rat Rattus norvegicus Q5MJ12 479 51833 L319 V V N V V H S L P N L T S L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425498 333 36281 Y232 V G D Q S L A Y I A Q G L D G
Frog Xenopus laevis NP_001083845 400 43783 Y299 V G D Q S L A Y I A Q G L Y G
Zebra Danio Brachydanio rerio NP_001015043 400 44429 Y299 I G D Q S L A Y I A Q G L Y Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523812 538 58367 F432 I N S L D V S F C D K I S D Q
Honey Bee Apis mellifera XP_393659 481 52936 F375 I S S L D V S F C D K I G D Q
Nematode Worm Caenorhab. elegans P34284 466 52046 G314 L K V L E L S G C T L L G D N
Sea Urchin Strong. purpuratus XP_784778 450 49952 F344 F A T L D A S F C D K I G D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5D2 610 66404 G355 L E R V E I N G C H N I G T R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.6 N.A. N.A. 95.6 21.2 N.A. N.A. 75.5 90.6 88.7 N.A. 46.2 54 25.5 63.5
Protein Similarity: 100 N.A. 96.6 N.A. N.A. 95.6 37.1 N.A. N.A. 77.9 93 92.1 N.A. 58.3 65.9 43.1 73.3
P-Site Identity: 100 N.A. 0 N.A. N.A. 26.6 0 N.A. N.A. 26.6 20 13.3 N.A. 26.6 26.6 40 20
P-Site Similarity: 100 N.A. 6.6 N.A. N.A. 33.3 40 N.A. N.A. 33.3 26.6 20 N.A. 40 40 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 26 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 17 34 0 0 34 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 9 0 50 0 0 0 0 0 0 % C
% Asp: 0 0 34 0 25 0 0 0 0 34 0 0 9 59 0 % D
% Glu: 0 9 0 0 17 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % F
% Gly: 0 34 0 0 0 0 0 25 0 0 9 34 34 0 34 % G
% His: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 0 % H
% Ile: 25 0 0 0 9 9 0 0 34 0 9 34 0 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 0 25 0 9 0 0 % K
% Leu: 25 9 0 42 0 50 0 9 9 0 17 17 34 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 0 0 9 0 0 9 9 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % P
% Gln: 0 0 0 34 0 0 9 0 0 0 34 0 0 0 25 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 9 9 25 0 42 0 42 9 0 0 0 9 17 9 9 % S
% Thr: 0 0 9 0 0 0 0 0 0 9 0 9 0 9 0 % T
% Val: 34 9 9 17 9 17 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 34 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _