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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL14
All Species:
4.85
Human Site:
S287
Identified Species:
9.7
UniProt:
Q8N1E6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1E6
NP_689654.1
418
45886
S287
R
L
S
G
L
D
V
S
F
C
D
K
V
G
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117874
404
44252
M276
T
G
I
M
H
L
A
M
G
S
L
R
L
S
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BID8
400
43846
M272
N
I
S
D
T
G
I
M
H
L
A
M
G
S
L
Rat
Rattus norvegicus
Q5MJ12
479
51833
Q292
L
A
Y
F
T
A
R
Q
G
H
S
T
H
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425498
333
36281
M205
N
I
S
D
T
G
I
M
H
L
A
M
G
S
L
Frog
Xenopus laevis
NP_001083845
400
43783
M272
N
I
S
D
T
G
I
M
H
L
A
M
G
S
L
Zebra Danio
Brachydanio rerio
NP_001015043
400
44429
M272
N
I
S
D
T
G
I
M
H
L
A
M
G
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523812
538
58367
R405
K
L
E
Q
L
N
L
R
S
C
D
N
I
S
D
Honey Bee
Apis mellifera
XP_393659
481
52936
R348
S
L
R
E
L
N
L
R
S
C
D
N
V
S
D
Nematode Worm
Caenorhab. elegans
P34284
466
52046
S287
A
L
E
Y
L
C
M
S
N
C
N
Q
I
S
D
Sea Urchin
Strong. purpuratus
XP_784778
450
49952
R317
S
L
R
E
L
N
L
R
S
C
D
N
I
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
S328
K
L
K
D
L
T
L
S
D
C
Y
F
V
S
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
N.A.
N.A.
95.6
21.2
N.A.
N.A.
75.5
90.6
88.7
N.A.
46.2
54
25.5
63.5
Protein Similarity:
100
N.A.
96.6
N.A.
N.A.
95.6
37.1
N.A.
N.A.
77.9
93
92.1
N.A.
58.3
65.9
43.1
73.3
P-Site Identity:
100
N.A.
0
N.A.
N.A.
6.6
0
N.A.
N.A.
6.6
6.6
6.6
N.A.
33.3
40
33.3
33.3
P-Site Similarity:
100
N.A.
13.3
N.A.
N.A.
20
0
N.A.
N.A.
20
20
20
N.A.
60
53.3
60
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
9
9
0
0
0
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
50
0
0
0
0
9
% C
% Asp:
0
0
0
42
0
9
0
0
9
0
34
0
0
0
42
% D
% Glu:
0
0
17
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% F
% Gly:
0
9
0
9
0
34
0
0
17
0
0
0
34
9
9
% G
% His:
0
0
0
0
9
0
0
0
34
9
0
0
9
0
0
% H
% Ile:
0
34
9
0
0
0
34
0
0
0
0
0
25
0
0
% I
% Lys:
17
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
9
50
0
0
50
9
34
0
0
34
9
0
9
0
42
% L
% Met:
0
0
0
9
0
0
9
42
0
0
0
34
0
0
0
% M
% Asn:
34
0
0
0
0
25
0
0
9
0
9
25
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
0
9
0
0
0
% Q
% Arg:
9
0
17
0
0
0
9
25
0
0
0
9
0
0
0
% R
% Ser:
17
0
42
0
0
0
0
25
25
9
9
0
0
75
0
% S
% Thr:
9
0
0
0
42
9
0
0
0
0
0
9
0
17
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _