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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL14
All Species:
4.85
Human Site:
S267
Identified Species:
9.7
UniProt:
Q8N1E6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1E6
NP_689654.1
418
45886
S267
L
R
S
C
D
N
I
S
D
T
G
I
M
H
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117874
404
44252
R256
L
S
H
M
G
S
L
R
S
L
N
L
R
S
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BID8
400
43846
M252
G
L
L
H
L
S
H
M
G
S
L
R
S
L
N
Rat
Rattus norvegicus
Q5MJ12
479
51833
E272
Q
L
L
P
N
L
A
E
L
S
L
Q
A
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425498
333
36281
M185
G
L
L
H
L
S
H
M
S
S
L
R
S
L
N
Frog
Xenopus laevis
NP_001083845
400
43783
M252
G
L
L
H
L
S
H
M
G
G
L
R
S
L
N
Zebra Danio
Brachydanio rerio
NP_001015043
400
44429
M252
G
M
I
H
L
S
H
M
T
S
L
W
S
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523812
538
58367
V385
N
L
S
F
C
V
S
V
T
D
S
G
L
K
H
Honey Bee
Apis mellifera
XP_393659
481
52936
I328
N
L
S
F
C
V
C
I
T
D
S
G
L
K
H
Nematode Worm
Caenorhab. elegans
P34284
466
52046
T267
L
L
Q
C
F
Q
L
T
D
I
T
V
Q
N
I
Sea Urchin
Strong. purpuratus
XP_784778
450
49952
I297
N
L
S
F
C
C
G
I
T
D
T
G
M
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
T308
L
Y
S
F
Q
H
F
T
D
K
G
M
R
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
N.A.
N.A.
95.6
21.2
N.A.
N.A.
75.5
90.6
88.7
N.A.
46.2
54
25.5
63.5
Protein Similarity:
100
N.A.
96.6
N.A.
N.A.
95.6
37.1
N.A.
N.A.
77.9
93
92.1
N.A.
58.3
65.9
43.1
73.3
P-Site Identity:
100
N.A.
6.6
N.A.
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
6.6
6.6
20
13.3
P-Site Similarity:
100
N.A.
26.6
N.A.
N.A.
13.3
20
N.A.
N.A.
13.3
6.6
13.3
N.A.
13.3
13.3
53.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
17
25
9
9
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
9
0
0
0
25
25
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
34
9
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
0
0
9
0
9
0
17
9
17
25
0
0
0
% G
% His:
0
0
9
34
0
9
34
0
0
0
0
0
0
9
25
% H
% Ile:
0
0
9
0
0
0
9
17
0
9
0
9
0
9
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
17
0
% K
% Leu:
34
67
34
0
34
9
17
0
9
9
42
9
17
34
9
% L
% Met:
0
9
0
9
0
0
0
34
0
0
0
9
17
0
0
% M
% Asn:
25
0
0
0
9
9
0
0
0
0
9
0
0
9
34
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
9
9
0
0
0
0
0
9
9
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
0
0
0
25
17
0
0
% R
% Ser:
0
9
42
0
0
42
9
9
17
34
17
0
34
9
9
% S
% Thr:
0
0
0
0
0
0
0
17
34
9
17
0
0
0
0
% T
% Val:
0
0
0
0
0
17
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _