KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIK1L
All Species:
4.55
Human Site:
S180
Identified Species:
11.11
UniProt:
Q8N165
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N165
NP_690048.1
341
38546
S180
S
Q
T
R
L
D
T
S
D
L
E
P
T
L
K
Chimpanzee
Pan troglodytes
XP_514467
401
44527
L244
E
R
S
G
T
P
I
L
K
V
A
D
F
G
L
Rhesus Macaque
Macaca mulatta
XP_001113747
401
44543
L244
E
R
S
G
T
P
I
L
K
V
A
D
F
G
L
Dog
Lupus familis
XP_851782
464
50954
L307
E
R
S
G
T
P
I
L
K
V
A
D
F
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZR7
341
38531
S180
S
Q
S
R
M
D
T
S
D
L
E
P
T
L
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516241
413
45927
D252
Q
S
R
A
D
S
S
D
S
E
P
T
L
K
V
Chicken
Gallus gallus
Q5ZJH6
468
53047
F264
K
R
I
S
F
E
E
F
F
A
H
P
F
V
D
Frog
Xenopus laevis
Q6NU47
339
38504
G178
L
V
C
K
S
R
D
G
V
D
E
P
T
L
K
Zebra Danio
Brachydanio rerio
Q32PP3
341
38186
G180
S
Q
G
R
T
P
A
G
S
P
E
P
T
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61267
476
54243
N314
D
N
V
L
L
E
T
N
D
E
E
T
L
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.5
59.5
51.5
N.A.
99.4
N.A.
N.A.
77.9
20.5
82.9
82.6
N.A.
20.3
N.A.
N.A.
N.A.
Protein Similarity:
100
71.5
71.5
62
N.A.
100
N.A.
N.A.
81.3
37.6
92.9
91.7
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
0
N.A.
86.6
N.A.
N.A.
0
6.6
33.3
53.3
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
20
N.A.
100
N.A.
N.A.
6.6
26.6
40
53.3
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
10
30
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
20
10
10
30
10
0
30
0
0
10
% D
% Glu:
30
0
0
0
0
20
10
0
0
20
50
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
10
10
0
0
0
40
0
0
% F
% Gly:
0
0
10
30
0
0
0
20
0
0
0
0
0
30
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
30
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
30
0
0
0
0
10
50
% K
% Leu:
10
0
0
10
20
0
0
30
0
20
0
0
20
50
30
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
40
0
0
0
10
10
50
0
0
0
% P
% Gln:
10
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
40
10
30
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
30
10
40
10
10
10
10
20
20
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
40
0
30
0
0
0
0
20
40
0
0
% T
% Val:
0
10
10
0
0
0
0
0
10
30
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _