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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGS
All Species:
28.18
Human Site:
Y407
Identified Species:
88.57
UniProt:
Q8N159
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N159
NP_694551.1
534
58156
Y407
G
K
K
L
R
D
D
Y
L
A
S
L
R
P
R
Chimpanzee
Pan troglodytes
XP_001152548
534
58083
Y407
G
K
K
L
R
D
D
Y
L
A
S
L
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001114030
534
58064
Y407
G
K
K
L
R
D
D
Y
L
A
S
L
R
P
R
Dog
Lupus familis
XP_548066
537
58241
Y410
G
K
K
L
R
D
D
Y
L
A
S
L
R
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4H7
527
57470
Y400
G
K
K
L
R
E
D
Y
L
E
S
L
R
P
R
Rat
Rattus norvegicus
NP_001100523
527
57402
Y400
G
K
K
L
R
E
D
Y
L
E
S
L
R
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685919
527
58389
Y392
E
K
N
L
R
E
D
Y
I
A
S
L
E
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796101
513
57176
Y387
G
R
V
L
K
K
N
Y
I
L
E
L
P
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97
87.9
N.A.
85.5
85.5
N.A.
N.A.
N.A.
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
32
Protein Similarity:
100
99.8
97.7
90.6
N.A.
90.4
90
N.A.
N.A.
N.A.
N.A.
64.7
N.A.
N.A.
N.A.
N.A.
52
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
63
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
50
88
0
0
0
0
0
0
0
0
% D
% Glu:
13
0
0
0
0
38
0
0
0
25
13
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
88
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% I
% Lys:
0
88
75
0
13
13
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
100
0
0
0
0
75
13
0
100
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
13
75
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
13
0
0
88
0
0
0
0
0
0
0
75
13
100
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
88
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _