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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAGS
All Species:
22.73
Human Site:
S341
Identified Species:
71.43
UniProt:
Q8N159
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N159
NP_694551.1
534
58156
S341
R
L
I
V
D
V
L
S
R
L
P
H
H
S
S
Chimpanzee
Pan troglodytes
XP_001152548
534
58083
S341
R
L
I
V
D
V
L
S
R
L
P
H
H
S
S
Rhesus Macaque
Macaca mulatta
XP_001114030
534
58064
S341
R
L
I
V
D
V
L
S
R
L
P
H
H
S
S
Dog
Lupus familis
XP_548066
537
58241
S344
R
L
I
V
D
V
L
S
R
L
P
H
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4H7
527
57470
S334
R
L
I
V
D
V
L
S
R
L
P
H
Y
S
S
Rat
Rattus norvegicus
NP_001100523
527
57402
S334
R
L
I
V
D
V
L
S
R
L
P
H
Y
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685919
527
58389
N326
G
S
I
A
E
L
L
N
L
L
P
V
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796101
513
57176
E321
Q
D
I
S
T
M
L
E
A
L
P
S
M
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97
87.9
N.A.
85.5
85.5
N.A.
N.A.
N.A.
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
32
Protein Similarity:
100
99.8
97.7
90.6
N.A.
90.4
90
N.A.
N.A.
N.A.
N.A.
64.7
N.A.
N.A.
N.A.
N.A.
52
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
75
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
13
0
0
13
0
0
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
75
50
0
0
% H
% Ile:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
75
0
0
0
13
100
0
13
100
0
0
0
0
0
% L
% Met:
0
0
0
0
0
13
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
75
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% R
% Ser:
0
13
0
13
0
0
0
75
0
0
0
13
0
100
100
% S
% Thr:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
75
0
75
0
0
0
0
0
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _