KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUSL1
All Species:
15.15
Human Site:
Y231
Identified Species:
25.64
UniProt:
Q8N0Z8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0Z8
NP_699170.1
303
33233
Y231
F
E
S
Q
S
F
L
Y
R
Q
V
R
R
M
T
Chimpanzee
Pan troglodytes
XP_513709
293
32103
A225
G
Q
A
R
A
V
T
A
A
W
G
P
Q
H
C
Rhesus Macaque
Macaca mulatta
XP_001093509
505
54336
Y433
F
E
S
Q
S
F
L
Y
R
Q
V
R
R
M
T
Dog
Lupus familis
XP_546716
294
32482
F226
L
E
F
E
S
R
S
F
L
Y
R
Q
V
R
R
Cat
Felis silvestris
Mouse
Mus musculus
A2ADA5
291
31974
L222
R
R
L
Q
F
W
T
L
E
F
E
S
Q
S
F
Rat
Rattus norvegicus
NP_001102169
127
14145
E59
R
L
Q
F
W
T
L
E
F
E
S
Q
S
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417580
291
32818
S221
F
W
E
L
K
F
K
S
R
S
F
L
Y
R
Q
Frog
Xenopus laevis
Q6GQ53
298
33665
Y224
F
R
A
R
S
F
L
Y
K
Q
V
R
R
M
T
Zebra Danio
Brachydanio rerio
XP_683563
290
32910
S219
F
W
E
L
T
F
K
S
R
S
F
L
Y
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036574
306
35200
W236
A
A
E
T
Y
N
Y
W
D
I
E
I
R
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781664
306
35062
Y229
F
H
S
R
S
F
L
Y
K
Q
I
R
R
M
T
Poplar Tree
Populus trichocarpa
XP_002331109
326
36158
K225
G
P
H
S
F
H
N
K
C
K
T
G
L
P
T
Maize
Zea mays
NP_001146958
386
42294
P284
S
L
V
Y
S
R
K
P
D
M
E
S
S
G
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172451
372
41526
Q274
D
P
L
A
C
S
N
Q
P
K
S
E
T
A
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
46.7
78.8
N.A.
76.9
35.3
N.A.
N.A.
50.1
50.1
46.2
N.A.
30.3
N.A.
N.A.
42.8
Protein Similarity:
100
74.9
52.4
83.1
N.A.
83.8
36.6
N.A.
N.A.
64.3
66.6
62.3
N.A.
50.9
N.A.
N.A.
60.4
P-Site Identity:
100
0
100
13.3
N.A.
6.6
6.6
N.A.
N.A.
20
73.3
20
N.A.
6.6
N.A.
N.A.
73.3
P-Site Similarity:
100
33.3
100
33.3
N.A.
20
20
N.A.
N.A.
20
93.3
26.6
N.A.
13.3
N.A.
N.A.
93.3
Percent
Protein Identity:
33.4
28.7
N.A.
27.9
N.A.
N.A.
Protein Similarity:
50.3
41.7
N.A.
44.8
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
6.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
8
0
0
8
8
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% D
% Glu:
0
22
22
8
0
0
0
8
8
8
22
8
0
0
0
% E
% Phe:
43
0
8
8
15
43
0
8
8
8
15
0
0
8
8
% F
% Gly:
15
0
0
0
0
0
0
0
0
0
8
8
0
8
8
% G
% His:
0
8
8
0
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% I
% Lys:
0
0
0
0
8
0
22
8
15
15
0
0
0
0
15
% K
% Leu:
8
15
15
15
0
0
36
8
8
0
0
15
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
29
0
% M
% Asn:
0
0
0
0
0
8
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
0
0
0
0
0
8
8
0
0
8
0
8
0
% P
% Gln:
0
8
8
22
0
0
0
8
0
29
0
15
15
0
15
% Q
% Arg:
15
15
0
22
0
15
0
0
29
0
8
29
36
22
8
% R
% Ser:
8
0
22
8
43
8
8
15
0
15
15
15
15
8
0
% S
% Thr:
0
0
0
8
8
8
15
0
0
0
8
0
8
0
36
% T
% Val:
0
0
8
0
0
8
0
0
0
0
22
0
8
0
0
% V
% Trp:
0
15
0
0
8
8
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
8
29
0
8
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _