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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUSL1
All Species:
7.88
Human Site:
S260
Identified Species:
13.33
UniProt:
Q8N0Z8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0Z8
NP_699170.1
303
33233
S260
Q
V
K
T
I
L
E
S
Q
D
P
L
G
K
H
Chimpanzee
Pan troglodytes
XP_513709
293
32103
S251
S
Q
H
P
G
C
P
S
L
S
Q
A
G
W
G
Rhesus Macaque
Macaca mulatta
XP_001093509
505
54336
S462
Q
V
K
T
I
L
E
S
Q
D
P
L
G
K
H
Dog
Lupus familis
XP_546716
294
32482
K252
A
L
R
P
A
Q
V
K
V
I
L
E
S
R
D
Cat
Felis silvestris
Mouse
Mus musculus
A2ADA5
291
31974
I248
L
V
A
V
G
L
G
I
L
A
P
T
Q
V
K
Rat
Rattus norvegicus
NP_001102169
127
14145
L85
V
A
V
G
L
G
I
L
A
P
T
Q
V
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417580
291
32818
I249
G
K
L
A
P
H
H
I
K
E
L
L
E
M
K
Frog
Xenopus laevis
Q6GQ53
298
33665
N253
Q
I
K
E
F
L
E
N
Q
D
P
N
C
F
L
Zebra Danio
Brachydanio rerio
XP_683563
290
32910
K246
Q
G
R
L
S
V
S
K
I
Q
D
L
L
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036574
306
35200
R264
L
I
A
L
G
N
G
R
I
D
E
R
C
L
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781664
306
35062
S258
H
I
T
T
I
L
E
S
R
D
N
S
H
M
H
Poplar Tree
Populus trichocarpa
XP_002331109
326
36158
H258
G
F
G
I
R
R
R
H
R
C
Y
V
I
T
A
Maize
Zea mays
NP_001146958
386
42294
V334
R
S
F
L
Y
H
Q
V
R
L
M
V
G
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172451
372
41526
A327
Q
V
R
L
I
V
G
A
L
K
C
V
G
T
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
46.7
78.8
N.A.
76.9
35.3
N.A.
N.A.
50.1
50.1
46.2
N.A.
30.3
N.A.
N.A.
42.8
Protein Similarity:
100
74.9
52.4
83.1
N.A.
83.8
36.6
N.A.
N.A.
64.3
66.6
62.3
N.A.
50.9
N.A.
N.A.
60.4
P-Site Identity:
100
13.3
100
0
N.A.
20
6.6
N.A.
N.A.
6.6
46.6
13.3
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
13.3
100
20
N.A.
20
13.3
N.A.
N.A.
20
60
33.3
N.A.
20
N.A.
N.A.
60
Percent
Protein Identity:
33.4
28.7
N.A.
27.9
N.A.
N.A.
Protein Similarity:
50.3
41.7
N.A.
44.8
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
13.3
33.3
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
8
0
0
8
8
8
0
8
0
0
15
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
8
0
15
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
36
8
0
0
0
8
% D
% Glu:
0
0
0
8
0
0
29
0
0
8
8
8
8
8
0
% E
% Phe:
0
8
8
0
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
15
8
8
8
22
8
22
0
0
0
0
0
36
0
15
% G
% His:
8
0
8
0
0
15
8
8
0
0
0
0
8
0
22
% H
% Ile:
0
22
0
8
29
0
8
15
15
8
0
0
8
0
0
% I
% Lys:
0
8
22
0
0
0
0
15
8
8
0
0
0
22
15
% K
% Leu:
15
8
8
29
8
36
0
8
22
8
15
29
8
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
15
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
15
8
0
8
0
0
8
29
0
0
0
0
% P
% Gln:
36
8
0
0
0
8
8
0
22
8
8
8
8
0
0
% Q
% Arg:
8
0
22
0
8
8
8
8
22
0
0
8
0
8
0
% R
% Ser:
8
8
0
0
8
0
8
29
0
8
0
8
8
0
0
% S
% Thr:
0
0
8
22
0
0
0
0
0
0
8
8
0
15
0
% T
% Val:
8
29
8
8
0
15
8
8
8
0
0
22
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _