KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUSL1
All Species:
9.39
Human Site:
S199
Identified Species:
15.9
UniProt:
Q8N0Z8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0Z8
NP_699170.1
303
33233
S199
V
R
T
L
R
R
V
S
V
S
P
G
Q
A
S
Chimpanzee
Pan troglodytes
XP_513709
293
32103
R193
S
P
V
P
S
P
V
R
T
L
R
R
V
S
V
Rhesus Macaque
Macaca mulatta
XP_001093509
505
54336
S401
V
R
T
L
R
R
V
S
V
S
P
G
Q
A
S
Dog
Lupus familis
XP_546716
294
32482
R194
T
S
S
V
R
T
L
R
R
A
S
V
S
P
D
Cat
Felis silvestris
Mouse
Mus musculus
A2ADA5
291
31974
N190
S
A
G
S
P
V
T
N
T
V
R
T
L
R
R
Rat
Rattus norvegicus
NP_001102169
127
14145
A27
A
G
S
P
V
P
H
A
V
R
T
L
R
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417580
291
32818
K189
T
P
F
R
S
P
V
K
T
I
L
Q
A
D
I
Frog
Xenopus laevis
Q6GQ53
298
33665
A192
P
I
K
T
L
Q
Q
A
D
I
N
P
S
C
G
Zebra Danio
Brachydanio rerio
XP_683563
290
32910
V187
D
A
P
F
K
C
P
V
K
T
L
D
L
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036574
306
35200
F204
V
C
R
D
H
P
M
F
T
V
R
K
I
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781664
306
35062
E197
I
K
T
I
D
M
I
E
F
R
R
T
R
G
F
Poplar Tree
Populus trichocarpa
XP_002331109
326
36158
S193
F
R
T
L
E
E
L
S
V
L
E
V
V
S
T
Maize
Zea mays
NP_001146958
386
42294
S252
V
R
T
L
D
E
L
S
V
T
E
V
F
P
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172451
372
41526
N242
M
R
S
L
D
E
L
N
I
T
E
V
P
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
46.7
78.8
N.A.
76.9
35.3
N.A.
N.A.
50.1
50.1
46.2
N.A.
30.3
N.A.
N.A.
42.8
Protein Similarity:
100
74.9
52.4
83.1
N.A.
83.8
36.6
N.A.
N.A.
64.3
66.6
62.3
N.A.
50.9
N.A.
N.A.
60.4
P-Site Identity:
100
6.6
100
6.6
N.A.
0
6.6
N.A.
N.A.
6.6
0
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
33.3
N.A.
6.6
26.6
N.A.
N.A.
6.6
13.3
20
N.A.
13.3
N.A.
N.A.
40
Percent
Protein Identity:
33.4
28.7
N.A.
27.9
N.A.
N.A.
Protein Similarity:
50.3
41.7
N.A.
44.8
N.A.
N.A.
P-Site Identity:
33.3
40
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
53.3
53.3
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
0
0
0
15
0
8
0
0
8
22
0
% A
% Cys:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
8
22
0
0
0
8
0
0
8
0
15
8
% D
% Glu:
0
0
0
0
8
22
0
8
0
0
22
0
0
0
8
% E
% Phe:
8
0
8
8
0
0
0
8
8
0
0
0
8
0
15
% F
% Gly:
0
8
8
0
0
0
0
0
0
0
0
15
0
8
8
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
0
0
8
0
8
15
0
0
8
0
8
% I
% Lys:
0
8
8
0
8
0
0
8
8
0
0
8
0
0
0
% K
% Leu:
0
0
0
36
8
0
29
0
0
15
15
8
15
0
0
% L
% Met:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
8
0
0
0
0
% N
% Pro:
8
15
8
15
8
29
8
0
0
0
15
8
8
15
0
% P
% Gln:
0
0
0
0
0
8
8
0
0
0
0
8
15
0
8
% Q
% Arg:
0
36
8
8
22
15
0
15
8
15
29
8
15
15
8
% R
% Ser:
15
8
22
8
15
0
0
29
0
15
8
0
15
22
15
% S
% Thr:
15
0
36
8
0
8
8
0
29
22
8
15
0
0
15
% T
% Val:
29
0
8
8
8
8
29
8
36
15
0
29
15
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _