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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC5
All Species:
18.79
Human Site:
S427
Identified Species:
37.58
UniProt:
Q8N0Z6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0Z6
NP_612385.2
440
48928
S427
G
K
P
Q
G
S
S
S
Q
A
V
A
T
V
A
Chimpanzee
Pan troglodytes
XP_520664
440
48965
S427
G
K
P
Q
G
S
S
S
Q
A
V
A
T
V
A
Rhesus Macaque
Macaca mulatta
XP_001091691
320
36000
Q308
K
P
Q
G
S
S
S
Q
A
V
A
T
V
A
S
Dog
Lupus familis
XP_853663
486
53619
S473
G
K
P
Q
G
P
S
S
Q
A
A
A
T
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG4
440
48779
S427
G
K
P
Q
N
S
S
S
Q
A
S
A
T
V
A
Rat
Rattus norvegicus
Q5BK48
440
48775
S427
G
K
P
Q
N
S
S
S
Q
A
S
A
T
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515437
114
12297
K102
S
G
A
V
A
L
G
K
V
L
F
S
L
T
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017654
446
49645
S433
G
K
R
Q
V
M
K
S
Q
S
A
A
F
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394646
430
49125
Q417
G
R
K
L
G
R
E
Q
E
A
S
A
K
L
H
Nematode Worm
Caenorhab. elegans
NP_490922
402
45164
E389
K
N
G
V
P
L
P
E
S
V
L
A
R
A
V
Sea Urchin
Strong. purpuratus
XP_784804
627
69496
K614
G
K
K
L
G
I
D
K
Q
A
P
A
T
V
S
Poplar Tree
Populus trichocarpa
XP_002314823
392
43949
G380
Q
T
C
L
Q
N
F
G
Q
S
M
K
D
E
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
71.8
81.4
N.A.
90.4
90.2
N.A.
21.1
N.A.
N.A.
57.6
N.A.
N.A.
46.5
23.4
37
Protein Similarity:
100
100
72.5
87
N.A.
94.7
95
N.A.
23.8
N.A.
N.A.
74.4
N.A.
N.A.
63.4
45.9
50.4
P-Site Identity:
100
100
13.3
86.6
N.A.
86.6
86.6
N.A.
0
N.A.
N.A.
46.6
N.A.
N.A.
26.6
6.6
53.3
P-Site Similarity:
100
100
20
86.6
N.A.
86.6
86.6
N.A.
6.6
N.A.
N.A.
53.3
N.A.
N.A.
46.6
13.3
60
Percent
Protein Identity:
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
9
59
25
75
0
17
42
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
9
9
9
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
9
0
9
0
0
% F
% Gly:
67
9
9
9
42
0
9
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
59
17
0
0
0
9
17
0
0
0
9
9
0
0
% K
% Leu:
0
0
0
25
0
17
0
0
0
9
9
0
9
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
0
17
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
42
0
9
9
9
0
0
0
9
0
0
0
0
% P
% Gln:
9
0
9
50
9
0
0
17
67
0
0
0
0
0
0
% Q
% Arg:
0
9
9
0
0
9
0
0
0
0
0
0
9
0
0
% R
% Ser:
9
0
0
0
9
42
50
50
9
17
25
9
0
0
17
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
9
50
9
25
% T
% Val:
0
0
0
17
9
0
0
0
9
17
17
0
9
59
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _