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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC5
All Species:
13.03
Human Site:
S276
Identified Species:
26.06
UniProt:
Q8N0Z6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0Z6
NP_612385.2
440
48928
S276
E
F
L
D
R
L
T
S
L
L
E
S
K
G
K
Chimpanzee
Pan troglodytes
XP_520664
440
48965
S276
E
F
L
D
R
L
T
S
L
L
E
S
K
G
K
Rhesus Macaque
Macaca mulatta
XP_001091691
320
36000
M162
D
E
H
S
H
H
V
M
D
S
V
R
Q
A
K
Dog
Lupus familis
XP_853663
486
53619
S322
E
F
L
S
R
L
T
S
L
L
E
S
K
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG4
440
48779
S276
E
F
L
S
R
L
T
S
L
L
E
S
K
G
K
Rat
Rattus norvegicus
Q5BK48
440
48775
N276
E
F
L
S
R
L
T
N
L
L
A
S
K
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515437
114
12297
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017654
446
49645
I282
N
Y
L
D
Q
V
T
I
L
L
E
N
K
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394646
430
49125
E268
T
P
R
N
K
R
D
E
L
L
Q
Y
L
K
D
Nematode Worm
Caenorhab. elegans
NP_490922
402
45164
K241
E
A
L
A
V
L
Q
K
A
V
E
Y
D
P
R
Sea Urchin
Strong. purpuratus
XP_784804
627
69496
E463
S
Y
L
A
R
I
T
E
L
T
K
A
K
G
K
Poplar Tree
Populus trichocarpa
XP_002314823
392
43949
F234
K
S
N
P
D
L
Y
F
N
C
A
T
V
N
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
71.8
81.4
N.A.
90.4
90.2
N.A.
21.1
N.A.
N.A.
57.6
N.A.
N.A.
46.5
23.4
37
Protein Similarity:
100
100
72.5
87
N.A.
94.7
95
N.A.
23.8
N.A.
N.A.
74.4
N.A.
N.A.
63.4
45.9
50.4
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
80
N.A.
0
N.A.
N.A.
60
N.A.
N.A.
13.3
26.6
46.6
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
N.A.
86.6
N.A.
N.A.
33.3
40
73.3
Percent
Protein Identity:
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
0
0
0
9
0
17
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
0
0
25
9
0
9
0
9
0
0
0
9
0
9
% D
% Glu:
50
9
0
0
0
0
0
17
0
0
50
0
0
0
0
% E
% Phe:
0
42
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
0
% G
% His:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
9
0
0
9
0
0
9
0
59
9
67
% K
% Leu:
0
0
67
0
0
59
0
0
67
59
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
9
0
0
0
9
9
0
0
9
0
9
0
% N
% Pro:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
9
0
9
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
9
0
50
9
0
0
0
0
0
9
0
0
17
% R
% Ser:
9
9
0
34
0
0
0
34
0
9
0
42
0
0
0
% S
% Thr:
9
0
0
0
0
0
59
0
0
9
0
9
0
0
0
% T
% Val:
0
0
0
0
9
9
9
0
0
9
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
9
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _