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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
36.36
Human Site:
Y832
Identified Species:
72.73
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
Y832
R
G
L
S
L
D
F
Y
Q
G
H
I
T
A
F
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
Y917
D
G
L
A
L
N
F
Y
E
G
Q
I
T
S
F
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
Y832
R
G
L
S
L
D
F
Y
Q
G
H
I
T
A
F
Dog
Lupus familis
XP_538773
2261
253895
Y924
D
G
L
A
L
N
F
Y
E
G
Q
I
T
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
Y829
Q
G
L
N
L
D
F
Y
E
G
H
I
T
A
F
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
Y830
R
G
L
N
L
D
F
Y
E
G
H
I
T
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
Y929
D
G
L
A
L
N
F
Y
E
G
Q
I
T
S
F
Chicken
Gallus gallus
NP_989476
2260
254054
Y925
D
G
L
T
L
N
F
Y
E
G
Q
I
T
S
F
Frog
Xenopus laevis
NP_001089022
2363
267334
Y1022
D
R
M
N
I
T
F
Y
E
G
Q
I
T
A
F
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
Y928
D
G
L
T
L
G
F
Y
E
G
Q
I
T
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
G585
L
L
G
H
N
G
A
G
K
S
T
T
F
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
C762
M
A
N
G
S
L
K
C
C
G
S
S
I
F
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
60
100
60
N.A.
80
86.6
N.A.
60
60
46.6
60
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
86.6
100
86.6
N.A.
100
100
N.A.
86.6
86.6
73.3
80
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
25
0
0
9
0
0
0
0
0
0
42
0
% A
% Cys:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
84
0
0
0
0
0
9
9
84
% F
% Gly:
0
75
9
9
0
17
0
9
0
92
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
34
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
84
9
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% K
% Leu:
9
9
75
0
75
9
0
0
0
0
0
0
0
0
9
% L
% Met:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
25
9
34
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
17
0
50
0
0
0
0
% Q
% Arg:
25
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
17
9
0
0
0
0
9
9
9
0
50
9
% S
% Thr:
0
0
0
17
0
9
0
0
0
0
9
9
84
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _