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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
36.36
Human Site:
T580
Identified Species:
72.73
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
T580
K
E
T
R
L
R
D
T
M
R
A
M
G
L
S
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
T663
K
E
A
R
L
K
E
T
M
R
I
M
G
L
D
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
T580
K
E
T
R
L
R
D
T
M
R
A
M
G
L
S
Dog
Lupus familis
XP_538773
2261
253895
T670
K
E
A
R
L
K
E
T
M
R
I
M
G
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
T577
K
E
T
R
L
R
E
T
M
R
A
M
G
L
S
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
T578
K
E
T
R
L
R
E
T
M
R
A
M
G
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
T675
K
E
A
R
L
K
E
T
M
R
I
M
G
L
D
Chicken
Gallus gallus
NP_989476
2260
254054
T671
K
E
A
R
L
K
E
T
M
R
I
M
G
L
D
Frog
Xenopus laevis
NP_001089022
2363
267334
T685
K
E
L
R
L
K
E
T
M
K
N
M
G
V
T
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
T674
K
E
A
R
L
K
E
T
M
R
I
M
G
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Y343
L
I
V
T
V
L
M
Y
G
L
G
A
V
I
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
I520
T
D
M
F
P
A
D
I
E
V
N
Q
G
E
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
66.6
100
66.6
N.A.
93.3
93.3
N.A.
66.6
66.6
53.3
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
80
100
80
N.A.
100
100
N.A.
80
80
86.6
80
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
0
0
9
0
0
0
0
34
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
25
0
0
0
0
0
0
0
42
% D
% Glu:
0
84
0
0
0
0
67
0
9
0
0
0
0
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
9
0
92
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
0
0
42
0
0
9
0
% I
% Lys:
84
0
0
0
0
50
0
0
0
9
0
0
0
0
0
% K
% Leu:
9
0
9
0
84
9
0
0
0
9
0
0
0
75
0
% L
% Met:
0
0
9
0
0
0
9
0
84
0
0
84
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
84
0
34
0
0
0
75
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% S
% Thr:
9
0
34
9
0
0
0
84
0
0
0
0
0
0
9
% T
% Val:
0
0
9
0
9
0
0
0
0
9
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _