KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
24.55
Human Site:
S417
Identified Species:
49.09
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
S417
D
K
L
E
A
A
P
S
E
A
A
L
V
S
R
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
T508
N
K
L
E
P
I
A
T
E
V
W
L
I
N
K
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
S417
D
K
L
E
A
A
P
S
E
A
A
L
V
S
R
Dog
Lupus familis
XP_538773
2261
253895
T515
N
K
L
E
P
V
A
T
E
V
R
L
I
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
S414
D
K
L
E
A
V
P
S
E
E
A
L
V
S
R
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
S414
D
K
L
E
A
V
P
S
E
E
A
L
V
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S520
D
K
L
E
P
V
S
S
E
G
R
L
I
N
K
Chicken
Gallus gallus
NP_989476
2260
254054
T516
D
K
L
E
P
V
A
T
E
V
R
L
I
N
K
Frog
Xenopus laevis
NP_001089022
2363
267334
D530
D
K
F
E
G
H
D
D
E
S
H
L
T
H
H
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
N519
D
K
L
E
P
V
A
N
E
E
R
L
V
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
P196
T
S
Y
N
P
Y
G
P
S
S
G
R
Y
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
M373
S
A
I
M
L
S
F
M
I
S
T
F
F
T
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
33.3
100
33.3
N.A.
86.6
86.6
N.A.
46.6
40
33.3
46.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
66.6
100
66.6
N.A.
86.6
86.6
N.A.
66.6
66.6
40
66.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
34
17
34
0
0
17
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
84
0
0
0
0
84
25
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
0
9
0
9
0
0
9
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
9
0
0
9
9
% H
% Ile:
0
0
9
0
0
9
0
0
9
0
0
0
34
0
0
% I
% Lys:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
42
% K
% Leu:
0
0
75
0
9
0
0
0
0
0
0
84
0
0
0
% L
% Met:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
9
0
0
0
9
0
0
0
0
0
42
0
% N
% Pro:
0
0
0
0
50
0
34
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
34
9
0
0
50
% R
% Ser:
9
9
0
0
0
9
9
42
9
25
0
0
0
42
0
% S
% Thr:
9
0
0
0
0
0
0
25
0
0
9
0
9
9
0
% T
% Val:
0
0
0
0
0
50
0
0
0
25
0
0
42
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _