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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
4.24
Human Site:
S182
Identified Species:
8.48
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
S182
Q
A
Q
E
P
L
H
S
L
L
E
A
A
E
D
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
V175
A
D
V
I
L
H
K
V
F
L
Q
G
Y
Q
L
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
S182
Q
A
Q
E
P
L
Q
S
L
L
E
A
A
E
D
Dog
Lupus familis
XP_538773
2261
253895
V182
A
N
V
S
L
H
K
V
F
L
Q
G
Y
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
K179
Q
A
Q
D
S
M
R
K
F
S
D
A
I
R
D
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
K179
Q
A
Q
D
S
M
R
K
F
S
D
A
T
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
V182
A
E
V
N
L
Q
Q
V
V
V
S
G
Y
R
M
Chicken
Gallus gallus
NP_989476
2260
254054
K182
D
A
E
V
N
L
Q
K
V
I
V
S
G
Y
R
Frog
Xenopus laevis
NP_001089022
2363
267334
I182
D
S
V
V
Y
Q
L
I
N
A
Q
I
R
V
E
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
V182
A
N
V
N
L
E
K
V
L
I
K
G
F
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
R166
H
L
F
D
Y
S
I
R
L
N
H
T
W
A
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
6.6
93.3
6.6
N.A.
33.3
26.6
N.A.
0
13.3
0
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
93.3
20
N.A.
53.3
46.6
N.A.
13.3
40
20
20
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
42
0
0
0
0
0
0
0
9
0
34
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
0
25
0
0
0
0
0
0
17
0
0
0
25
% D
% Glu:
0
9
9
17
0
9
0
0
0
0
17
0
0
17
9
% E
% Phe:
0
0
9
0
0
0
0
0
34
0
0
0
9
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
34
9
9
0
% G
% His:
9
0
0
0
0
17
9
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
9
0
17
0
9
9
0
0
% I
% Lys:
0
0
0
0
0
0
25
25
0
0
9
0
0
0
0
% K
% Leu:
0
9
0
0
34
25
9
0
34
34
0
0
0
0
17
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
17
0
17
9
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
34
0
34
0
0
17
25
0
0
0
25
0
0
17
0
% Q
% Arg:
0
0
0
0
0
0
17
9
0
0
0
0
9
25
9
% R
% Ser:
0
9
0
9
17
9
0
17
0
17
9
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
9
% T
% Val:
0
0
42
17
0
0
0
34
17
9
9
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
17
0
0
0
0
0
0
0
25
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _