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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
3.94
Human Site:
S1765
Identified Species:
7.88
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.55
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
S1765
L
P
Q
P
R
V
R
S
L
P
L
L
G
E
E
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
K1877
R
P
R
P
V
N
A
K
L
P
P
L
N
D
E
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
S1767
L
P
Q
P
K
V
R
S
L
P
P
L
G
L
E
Dog
Lupus familis
XP_538773
2261
253895
K1884
R
P
R
P
I
K
A
K
F
P
P
L
N
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
L1779
L
P
Q
S
K
P
R
L
L
P
P
L
G
E
E
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
L1790
L
P
Q
P
K
S
R
L
P
P
P
L
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
K1889
K
P
R
P
V
C
A
K
L
P
P
V
N
D
E
Chicken
Gallus gallus
NP_989476
2260
254054
K1883
K
P
R
P
V
Y
A
K
L
P
P
V
N
D
E
Frog
Xenopus laevis
NP_001089022
2363
267334
P1989
G
T
W
F
A
E
P
P
K
G
S
I
D
G
E
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
K1891
K
A
R
S
L
S
T
K
L
K
P
I
G
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
F1407
A
V
D
Q
K
E
C
F
G
L
L
G
V
N
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
K1585
D
L
L
K
H
S
H
K
P
S
F
T
L
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
40
80
33.3
N.A.
66.6
66.6
N.A.
33.3
33.3
6.6
26.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
53.3
86.6
46.6
N.A.
73.3
73.3
N.A.
53.3
53.3
13.3
40
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
34
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
0
0
0
0
0
9
34
0
% D
% Glu:
0
0
0
0
0
17
0
0
0
0
0
0
0
34
84
% E
% Phe:
0
0
0
9
0
0
0
9
9
0
9
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
9
9
0
9
42
9
17
% G
% His:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
17
0
0
0
% I
% Lys:
25
0
0
9
34
9
0
50
9
9
0
0
0
0
0
% K
% Leu:
34
9
9
0
9
0
0
17
59
9
17
50
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
34
9
0
% N
% Pro:
0
67
0
59
0
9
9
9
17
67
67
0
0
0
0
% P
% Gln:
0
0
34
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
42
0
9
0
34
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
17
0
25
0
17
0
9
9
0
0
9
0
% S
% Thr:
0
9
0
0
0
0
9
0
0
0
0
9
0
0
0
% T
% Val:
0
9
0
0
25
17
0
0
0
0
0
17
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _