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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
30.61
Human Site:
S1723
Identified Species:
61.21
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
S1723
L
G
D
R
Q
F
Q
S
P
L
R
W
E
V
V
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
S1835
F
G
E
N
R
F
V
S
P
L
S
W
D
L
V
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
S1725
L
G
D
R
Q
F
Q
S
P
L
R
W
E
V
V
Dog
Lupus familis
XP_538773
2261
253895
S1842
F
G
E
N
R
F
V
S
P
L
S
W
D
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
S1737
L
G
D
K
Q
F
Q
S
P
L
R
W
D
I
I
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
S1748
L
G
D
K
Q
F
Q
S
P
L
R
W
D
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S1847
F
G
E
N
R
F
V
S
P
L
S
W
D
L
V
Chicken
Gallus gallus
NP_989476
2260
254054
S1841
F
G
E
N
R
F
V
S
P
L
S
W
D
L
V
Frog
Xenopus laevis
NP_001089022
2363
267334
N1947
F
G
E
E
H
I
S
N
P
F
Q
W
E
F
L
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
S1849
F
G
E
N
R
F
R
S
P
L
A
W
D
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Q1375
R
V
H
R
V
N
S
Q
N
S
A
L
V
I
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
E1553
L
T
V
K
E
H
L
E
L
Y
A
R
I
K
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
46.6
100
46.6
N.A.
73.3
73.3
N.A.
46.6
46.6
26.6
46.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
73.3
100
73.3
N.A.
100
100
N.A.
73.3
73.3
53.3
80
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
0
0
0
0
0
0
0
59
0
0
% D
% Glu:
0
0
50
9
9
0
0
9
0
0
0
0
25
0
0
% E
% Phe:
50
0
0
0
0
75
0
0
0
9
0
0
0
9
0
% F
% Gly:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
9
25
17
% I
% Lys:
0
0
0
25
0
0
0
0
0
0
0
0
0
9
9
% K
% Leu:
42
0
0
0
0
0
9
0
9
75
0
9
0
34
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
42
0
9
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
34
0
34
9
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
25
42
0
9
0
0
0
34
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
17
75
0
9
34
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
9
0
9
0
34
0
0
0
0
0
9
17
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _