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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
5.15
Human Site:
S1464
Identified Species:
10.3
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
S1464
N
L
T
A
W
A
H
S
L
D
A
Q
D
S
L
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
G1576
S
L
G
R
F
M
T
G
L
D
T
K
N
N
V
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
S1466
N
L
T
A
W
T
H
S
L
D
S
Q
D
S
L
Dog
Lupus familis
XP_538773
2261
253895
G1583
N
L
G
R
F
M
T
G
L
D
T
K
N
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
G1478
N
L
T
Q
W
A
L
G
L
D
A
R
N
S
L
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
G1489
N
L
T
Q
W
A
L
G
L
D
A
R
N
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
G1588
S
L
G
S
F
M
T
G
L
D
T
K
N
N
V
Chicken
Gallus gallus
NP_989476
2260
254054
G1582
N
L
A
S
F
M
K
G
L
D
T
K
N
N
V
Frog
Xenopus laevis
NP_001089022
2363
267334
Q1686
Q
E
L
Q
T
F
L
Q
H
L
E
T
E
D
N
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
G1590
S
L
S
T
F
I
R
G
L
D
T
N
N
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
C1151
F
L
I
E
E
R
T
C
Q
F
A
H
Q
Q
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
S1329
L
K
N
F
F
R
L
S
P
G
F
C
F
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
20
86.6
26.6
N.A.
66.6
66.6
N.A.
20
26.6
0
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
60
93.3
60
N.A.
80
80
N.A.
66.6
66.6
6.6
60
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
25
0
0
0
0
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
75
0
0
17
9
9
% D
% Glu:
0
9
0
9
9
0
0
0
0
0
9
0
9
0
0
% E
% Phe:
9
0
0
9
50
9
0
0
0
9
9
0
9
0
9
% F
% Gly:
0
0
25
0
0
0
0
59
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
17
0
9
0
0
9
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
9
0
0
0
0
34
0
0
0
% K
% Leu:
9
84
9
0
0
0
34
0
75
9
0
0
0
0
34
% L
% Met:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
9
0
0
0
0
0
0
0
0
9
59
42
9
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
0
0
25
0
0
0
9
9
0
0
17
9
9
0
% Q
% Arg:
0
0
0
17
0
17
9
0
0
0
0
17
0
0
0
% R
% Ser:
25
0
9
17
0
0
0
25
0
0
9
0
0
42
0
% S
% Thr:
0
0
34
9
9
9
34
0
0
0
42
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% V
% Trp:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _