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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CMTM8 All Species: 16.67
Human Site: S27 Identified Species: 40.74
UniProt: Q8IZV2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZV2 NP_849199.2 173 19572 S27 A E N F S T S S S S F A Y D R
Chimpanzee Pan troglodytes XP_516349 100 11395
Rhesus Macaque Macaca mulatta XP_001097523 173 19492 S27 A E N F S T S S S S F A Y D R
Dog Lupus familis XP_542744 173 19534 S27 A E N F S T S S S S F A Y D R
Cat Felis silvestris
Mouse Mus musculus Q9CZR4 173 19509 S27 A E N F S T T S S S F A Y D R
Rat Rattus norvegicus P47987 182 19815 M26 V G A S V S A M R P D L G F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521196 128 14730
Chicken Gallus gallus XP_418764 179 20124 S33 T A N L S A S S S T L A Y D R
Frog Xenopus laevis Q6GPN9 170 19203 G26 M E T I S L G G S I A Y D R S
Zebra Danio Brachydanio rerio Q5BLB7 162 18335 I21 F L K S F V G I V R V L Q I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.7 98.2 98.8 N.A. 92.4 40.1 N.A. 65.9 81 63.5 24.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57.7 99.4 99.4 N.A. 95.9 55.4 N.A. 71.6 88.2 76.8 41 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 0 N.A. 0 60 20 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 100 N.A. 100 13.3 N.A. 0 66.6 20 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 10 10 0 0 10 10 0 0 0 10 50 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 10 50 0 % D
% Glu: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 40 10 0 0 0 0 0 40 0 0 10 0 % F
% Gly: 0 10 0 0 0 0 20 10 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 10 0 10 0 0 0 10 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 0 10 0 0 0 0 10 20 0 0 10 % L
% Met: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 50 % R
% Ser: 0 0 0 20 60 10 40 50 60 40 0 0 0 0 10 % S
% Thr: 10 0 10 0 0 40 10 0 0 10 0 0 0 0 0 % T
% Val: 10 0 0 0 10 10 0 0 10 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _