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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HS3ST5
All Species:
29.39
Human Site:
Y147
Identified Species:
64.67
UniProt:
Q8IZT8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZT8
NP_705840.2
346
40408
Y147
R
K
K
M
P
F
S
Y
P
Q
Q
I
T
I
E
Chimpanzee
Pan troglodytes
XP_526526
307
35774
W111
L
S
Q
M
P
F
S
W
P
H
Q
L
T
V
E
Rhesus Macaque
Macaca mulatta
XP_001082139
346
40390
Y147
R
K
K
M
P
F
S
Y
P
Q
Q
I
T
I
E
Dog
Lupus familis
XP_539089
345
40397
Y146
R
K
K
M
P
F
S
Y
P
Q
Q
I
T
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSL4
346
40453
Y147
R
K
K
M
P
F
S
Y
P
Q
Q
I
T
I
E
Rat
Rattus norvegicus
Q9ESG5
311
35792
S115
L
T
Q
M
P
F
S
S
P
H
Q
L
T
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510276
345
40444
H146
R
R
K
M
P
F
S
H
P
H
Q
I
T
I
E
Chicken
Gallus gallus
XP_426178
345
40454
Y146
R
K
K
M
P
F
S
Y
P
H
Q
I
T
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074908
309
35901
Y113
R
E
Q
M
P
Y
S
Y
P
T
Q
I
T
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396407
369
42423
F149
R
R
K
M
P
Y
S
F
R
G
Q
I
T
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799088
345
40139
Y148
R
K
Q
M
P
F
S
Y
A
D
Q
I
T
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.1
99.4
97.9
N.A.
96.8
45.9
N.A.
92.4
93.6
N.A.
45.3
N.A.
N.A.
43.6
N.A.
43.3
Protein Similarity:
100
64.1
99.7
98.8
N.A.
97.6
62.7
N.A.
97.1
96.2
N.A.
60.9
N.A.
N.A.
60.1
N.A.
61.5
P-Site Identity:
100
53.3
100
100
N.A.
100
53.3
N.A.
80
93.3
N.A.
73.3
N.A.
N.A.
66.6
N.A.
73.3
P-Site Similarity:
100
80
100
100
N.A.
100
73.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
86.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
82
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
37
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
82
0
73
0
% I
% Lys:
0
55
64
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% L
% Met:
0
0
0
100
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
100
0
0
0
82
0
0
0
0
0
0
% P
% Gln:
0
0
37
0
0
0
0
0
0
37
100
0
0
0
0
% Q
% Arg:
82
19
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
100
10
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
0
100
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _