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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR116 All Species: 25.45
Human Site: S1295 Identified Species: 62.22
UniProt: Q8IZF2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZF2 NP_001091988.1 1346 149457 S1295 S Q H S K S T S L G S S T P V
Chimpanzee Pan troglodytes XP_001140861 1411 156356 S1360 S Q H S K S T S L G S S T P V
Rhesus Macaque Macaca mulatta XP_001103527 1338 148646 S1287 S Q H S K S T S L G S S T P V
Dog Lupus familis XP_532160 1363 151627 S1312 S Q H S K S T S L G S S T P V
Cat Felis silvestris
Mouse Mus musculus Q9D2L6 698 77313 F648 I F A L L N A F Q G F F I L L
Rat Rattus norvegicus Q9WVT0 1349 149427 S1298 S Q H S K S T S L G S S T P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511842 1375 151829 S1324 S Q H T K S T S L G S S T P V
Chicken Gallus gallus XP_420066 1320 147335 L1270 S H Q T F H I L F A L L N A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921201 820 91470 A770 M V I V R C V A F L T P I F G
Tiger Blowfish Takifugu rubipres NP_001092114 1678 181121 T1627 S K K S S T T T T G S N P T K
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 93.6 78.8 N.A. 24.2 73.2 N.A. 61.3 40.4 N.A. 23.7 24.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 95 96.2 86.5 N.A. 34.4 82.3 N.A. 74.1 57.7 N.A. 38.3 41.1 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 93.3 6.6 N.A. 0 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 100 N.A. 100 20 N.A. 20 60 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 10 0 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 10 0 0 10 20 0 10 10 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 10 % G
% His: 0 10 60 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 0 0 0 10 0 0 0 0 0 20 0 0 % I
% Lys: 0 10 10 0 60 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 10 10 0 0 10 60 10 10 10 0 10 20 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 10 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 10 60 0 % P
% Gln: 0 60 10 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 80 0 0 60 10 60 0 60 0 0 70 60 0 0 0 % S
% Thr: 0 0 0 20 0 10 70 10 10 0 10 0 60 10 0 % T
% Val: 0 10 0 10 0 0 10 0 0 0 0 0 0 0 60 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _