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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH16A1
All Species:
10
Human Site:
S604
Identified Species:
22
UniProt:
Q8IZ83
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ83
NP_699160.2
802
85127
S604
A
A
L
E
R
R
K
S
T
L
A
S
R
L
E
Chimpanzee
Pan troglodytes
XP_001172626
802
85017
S604
A
A
L
E
R
R
K
S
T
L
A
S
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001113116
323
33722
N164
Q
L
S
C
L
S
K
N
L
N
Y
D
T
F
G
Dog
Lupus familis
XP_851694
802
85494
S604
S
A
L
E
R
R
E
S
A
L
A
S
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q571I9
802
84737
P604
A
A
L
E
R
R
K
P
V
L
T
S
Q
L
E
Rat
Rattus norvegicus
Q3T1L0
802
85396
Q604
A
A
L
E
R
R
K
Q
V
L
A
A
Q
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519604
638
66871
F479
P
A
V
P
Y
G
L
F
L
G
G
K
F
Q
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089655
811
89363
D607
E
N
L
E
L
R
R
D
E
V
A
Q
R
L
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797815
831
90903
D627
E
N
L
E
Q
R
R
D
E
V
A
Q
G
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S795
501
54413
Y342
P
V
V
S
K
G
Q
Y
E
K
I
L
K
F
I
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
F360
D
P
F
D
E
E
V
F
Q
G
A
Q
T
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
38.7
84.9
N.A.
81.8
81
N.A.
49.2
N.A.
43.6
N.A.
N.A.
N.A.
N.A.
N.A.
41.1
Protein Similarity:
100
99.2
39.4
90.9
N.A.
88
87.9
N.A.
60.8
N.A.
61.1
N.A.
N.A.
N.A.
N.A.
N.A.
60.2
P-Site Identity:
100
100
6.6
80
N.A.
73.3
73.3
N.A.
6.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
80
86.6
N.A.
13.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.4
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
55
0
0
0
0
0
0
10
0
64
10
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
19
0
0
0
10
0
0
10
% D
% Glu:
19
0
0
64
10
10
10
0
28
0
0
0
0
0
46
% E
% Phe:
0
0
10
0
0
0
0
19
0
0
0
0
10
19
0
% F
% Gly:
0
0
0
0
0
19
0
0
0
19
10
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% I
% Lys:
0
0
0
0
10
0
46
0
0
10
0
10
10
0
0
% K
% Leu:
0
10
64
0
19
0
10
0
19
46
0
10
0
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
19
10
0
10
0
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
10
0
0
0
10
0
10
10
10
0
0
28
19
10
0
% Q
% Arg:
0
0
0
0
46
64
19
0
0
0
0
0
37
0
0
% R
% Ser:
10
0
10
10
0
10
0
28
0
0
0
37
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
19
0
10
0
19
0
0
% T
% Val:
0
10
19
0
0
0
10
0
19
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _