Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH16A1 All Species: 17.27
Human Site: S523 Identified Species: 38
UniProt: Q8IZ83 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ83 NP_699160.2 802 85127 S523 A G P E I G P S P A P P Y G L
Chimpanzee Pan troglodytes XP_001172626 802 85017 S523 A G P E I G P S P A P P Y G L
Rhesus Macaque Macaca mulatta XP_001113116 323 33722 G100 S V W S E R L G Q A L E L G Y
Dog Lupus familis XP_851694 802 85494 S523 A G P E I G P S P T A P Y G L
Cat Felis silvestris
Mouse Mus musculus Q571I9 802 84737 S523 S G P E T G P S P A P P Y G L
Rat Rattus norvegicus Q3T1L0 802 85396 S523 S G P E T G P S P A P P Y G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519604 638 66871 T415 L A L P F R T T K E A L A L A
Chicken Gallus gallus
Frog Xenopus laevis NP_001089655 811 89363 Q513 I P G Q K D I Q P S V I Q L Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797815 831 90903 V537 N P P A P S T V Q V D G F S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S795 501 54413 A278 D D V D L D K A A E W A L F G
Baker's Yeast Sacchar. cerevisiae P40047 520 56602 I296 L G G K S P N I V F A D A D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 38.7 84.9 N.A. 81.8 81 N.A. 49.2 N.A. 43.6 N.A. N.A. N.A. N.A. N.A. 41.1
Protein Similarity: 100 99.2 39.4 90.9 N.A. 88 87.9 N.A. 60.8 N.A. 61.1 N.A. N.A. N.A. N.A. N.A. 60.2
P-Site Identity: 100 100 13.3 86.6 N.A. 86.6 86.6 N.A. 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 20 86.6 N.A. 93.3 93.3 N.A. 6.6 N.A. 20 N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 21 21.4 N.A.
Protein Similarity: N.A. N.A. N.A. 32.4 35.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 10 0 10 0 0 0 10 10 46 28 10 19 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 10 0 19 0 0 0 0 10 10 0 10 0 % D
% Glu: 0 0 0 46 10 0 0 0 0 19 0 10 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 10 0 0 10 10 0 % F
% Gly: 0 55 19 0 0 46 0 10 0 0 0 10 0 55 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 28 0 10 10 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 10 0 10 0 10 0 0 0 0 0 0 % K
% Leu: 19 0 10 0 10 0 10 0 0 0 10 10 19 19 55 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 19 55 10 10 10 46 0 55 0 37 46 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 10 19 0 0 0 10 0 10 % Q
% Arg: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 0 0 10 10 10 0 46 0 10 0 0 0 10 0 % S
% Thr: 0 0 0 0 19 0 19 10 0 10 0 0 0 0 0 % T
% Val: 0 10 10 0 0 0 0 10 10 10 10 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 46 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _