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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH16A1
All Species:
26.36
Human Site:
S289
Identified Species:
58
UniProt:
Q8IZ83
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ83
NP_699160.2
802
85127
S289
T
D
T
A
D
V
D
S
A
V
E
G
V
V
D
Chimpanzee
Pan troglodytes
XP_001172626
802
85017
S289
T
D
T
A
D
I
D
S
A
V
E
G
V
V
D
Rhesus Macaque
Macaca mulatta
XP_001113116
323
33722
Dog
Lupus familis
XP_851694
802
85494
S289
T
E
A
A
D
V
D
S
A
V
E
G
V
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q571I9
802
84737
S289
T
D
S
A
D
V
D
S
A
V
E
G
V
V
D
Rat
Rattus norvegicus
Q3T1L0
802
85396
S289
T
D
S
A
D
V
D
S
A
V
E
G
V
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519604
638
66871
V199
L
A
V
G
C
S
V
V
V
L
S
A
G
S
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089655
811
89363
S274
F
D
T
S
D
L
D
S
A
V
E
G
I
V
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797815
831
90903
S298
F
E
S
A
D
L
D
S
A
V
E
G
I
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S795
501
54413
K62
R
R
A
L
S
R
N
K
G
K
D
W
A
K
A
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
E80
T
T
V
Y
K
A
M
E
D
D
V
D
E
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
38.7
84.9
N.A.
81.8
81
N.A.
49.2
N.A.
43.6
N.A.
N.A.
N.A.
N.A.
N.A.
41.1
Protein Similarity:
100
99.2
39.4
90.9
N.A.
88
87.9
N.A.
60.8
N.A.
61.1
N.A.
N.A.
N.A.
N.A.
N.A.
60.2
P-Site Identity:
100
93.3
0
86.6
N.A.
93.3
93.3
N.A.
0
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
0
93.3
N.A.
100
100
N.A.
6.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.4
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
55
0
10
0
0
64
0
0
10
10
10
19
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
64
0
64
0
10
10
10
10
0
0
64
% D
% Glu:
0
19
0
0
0
0
0
10
0
0
64
0
10
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
10
0
0
64
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
19
0
0
% I
% Lys:
0
0
0
0
10
0
0
10
0
10
0
0
0
10
0
% K
% Leu:
10
0
0
10
0
19
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
28
10
10
10
0
64
0
0
10
0
0
10
0
% S
% Thr:
55
10
28
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
19
0
0
37
10
10
10
64
10
0
46
64
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _