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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRMT2A
All Species:
18.18
Human Site:
S378
Identified Species:
36.36
UniProt:
Q8IZ69
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ69
NP_073564.3
625
68726
S378
E
G
Q
R
K
T
P
S
Q
E
G
L
P
L
E
Chimpanzee
Pan troglodytes
XP_001166807
625
68782
S378
E
G
Q
R
K
T
P
S
Q
E
G
L
P
L
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534759
667
72765
S419
E
G
Q
R
K
T
P
S
Q
E
G
L
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNV1
574
63283
S368
E
G
Q
R
K
T
P
S
Q
E
G
L
P
L
E
Rat
Rattus norvegicus
NP_001011895
615
67858
S369
E
G
Q
R
K
T
P
S
Q
E
G
L
P
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513281
481
53523
E279
P
Y
Q
L
L
S
G
E
P
Y
I
L
E
E
L
Chicken
Gallus gallus
XP_415080
602
66958
N336
E
G
Q
R
K
S
P
N
L
E
D
L
P
L
E
Frog
Xenopus laevis
NP_001093345
612
69426
L382
E
G
Q
R
K
S
P
L
L
E
D
L
P
V
E
Zebra Danio
Brachydanio rerio
A4QP75
473
53154
Q271
Q
Y
Q
L
L
Y
G
Q
T
H
I
Y
E
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649083
615
68596
A360
Q
D
V
K
H
R
E
A
G
Q
T
I
N
P
V
Honey Bee
Apis mellifera
XP_396538
568
64494
G347
M
K
I
K
S
I
D
G
K
D
E
E
N
F
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7S3
809
89004
L469
A
R
A
S
S
P
T
L
P
L
T
V
L
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
82.3
N.A.
77.5
82
N.A.
34.8
64.1
60.7
32.3
N.A.
36
33.9
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
85.6
N.A.
82.8
88
N.A.
48.3
76.9
75.6
45.9
N.A.
52.9
50.7
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
73.3
66.6
6.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
86.6
80
13.3
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
9
17
0
0
0
0
% D
% Glu:
59
0
0
0
0
0
9
9
0
59
9
9
17
17
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
59
0
0
0
0
17
9
9
0
42
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
17
9
0
0
0
% I
% Lys:
0
9
0
17
59
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
17
17
0
0
17
17
9
0
67
9
50
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
17
0
0
% N
% Pro:
9
0
0
0
0
9
59
0
17
0
0
0
59
9
0
% P
% Gln:
17
0
75
0
0
0
0
9
42
9
0
0
0
0
0
% Q
% Arg:
0
9
0
59
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
17
25
0
42
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
42
9
0
9
0
17
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
9
0
17
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
9
0
0
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _