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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASEF All Species: 15.15
Human Site: S507 Identified Species: 30.3
UniProt: Q8IZ41 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ41 NP_689786.2 740 82879 S507 W K P Q G S V S E G S I V S S
Chimpanzee Pan troglodytes XP_520093 989 110305 S756 W K P Q G S V S E G S I V S S
Rhesus Macaque Macaca mulatta XP_001104352 740 82761 S507 W K L Q G T V S E G S I V S S
Dog Lupus familis XP_541269 751 83654 S518 W K P H G S P S E G S V V S S
Cat Felis silvestris
Mouse Mus musculus Q5RI75 627 70734 S403 E G S T L S S S R K P I S A L
Rat Rattus norvegicus XP_001067187 709 79502 G477 G H P Q G S A G E G S T V S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511721 743 83385 L507 P N S P T T L L D W K P K G C
Chicken Gallus gallus XP_417952 297 32431 E73 L N V E K K Q E M E Q K M S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A5WW21 663 75839 S439 R S T V G S I S S S L R R R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VP48 388 43018 R164 D D Y N D G W R S Y R Y D E V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22908 656 74591 I432 I E E K T S L I L D D A H S L
Sea Urchin Strong. purpuratus XP_001177439 377 41472 E152 P T P S S S P E G Q R A E P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.1 95.8 85.7 N.A. 69.5 76 N.A. 72.8 20 N.A. 37.4 N.A. 21 N.A. 28.5 22.9
Protein Similarity: 100 74.5 97.4 90.2 N.A. 76.7 83.5 N.A. 83.4 29.7 N.A. 56.6 N.A. 31.6 N.A. 48.2 36.2
P-Site Identity: 100 100 86.6 80 N.A. 20 66.6 N.A. 0 6.6 N.A. 20 N.A. 0 N.A. 13.3 13.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 26.6 66.6 N.A. 20 20 N.A. 26.6 N.A. 0 N.A. 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 0 0 17 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 9 9 0 0 9 0 0 0 9 9 9 0 9 0 0 % D
% Glu: 9 9 9 9 0 0 0 17 42 9 0 0 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 0 0 50 9 0 9 9 42 0 0 0 9 0 % G
% His: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 0 0 0 9 9 0 0 0 34 0 0 0 % I
% Lys: 0 34 0 9 9 9 0 0 0 9 9 9 9 0 0 % K
% Leu: 9 0 9 0 9 0 17 9 9 0 9 0 0 0 34 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % M
% Asn: 0 17 0 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 17 0 42 9 0 0 17 0 0 0 9 9 0 9 0 % P
% Gln: 0 0 0 34 0 0 9 0 0 9 9 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 9 9 0 17 9 9 9 0 % R
% Ser: 0 9 17 9 9 67 9 50 17 9 42 0 9 59 42 % S
% Thr: 0 9 9 9 17 17 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 9 9 0 0 25 0 0 0 0 9 42 0 17 % V
% Trp: 34 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _