KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASEF
All Species:
18.18
Human Site:
S406
Identified Species:
36.36
UniProt:
Q8IZ41
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ41
NP_689786.2
740
82879
S406
Y
D
R
S
S
R
S
S
Y
V
D
E
D
C
D
Chimpanzee
Pan troglodytes
XP_520093
989
110305
S655
Y
D
R
S
S
R
S
S
Y
V
D
E
D
C
D
Rhesus Macaque
Macaca mulatta
XP_001104352
740
82761
S406
Y
D
R
S
S
R
S
S
Y
V
D
E
D
C
D
Dog
Lupus familis
XP_541269
751
83654
S417
Y
D
R
S
S
H
S
S
Y
M
D
E
D
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5RI75
627
70734
D302
S
Y
A
D
E
D
C
D
S
L
A
L
C
D
P
Rat
Rattus norvegicus
XP_001067187
709
79502
S376
Y
D
R
S
S
H
S
S
Y
A
D
E
D
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511721
743
83385
S406
Q
S
D
R
L
S
R
S
S
Y
M
D
E
D
C
Chicken
Gallus gallus
XP_417952
297
32431
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5WW21
663
75839
N338
K
R
Q
L
S
P
R
N
E
V
L
P
R
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP48
388
43018
P63
F
G
D
G
S
Y
N
P
P
A
A
P
A
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22908
656
74591
D331
I
N
S
L
S
S
S
D
Q
A
S
H
A
T
E
Sea Urchin
Strong. purpuratus
XP_001177439
377
41472
F51
H
L
Q
L
S
Q
S
F
M
Y
D
D
D
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
95.8
85.7
N.A.
69.5
76
N.A.
72.8
20
N.A.
37.4
N.A.
21
N.A.
28.5
22.9
Protein Similarity:
100
74.5
97.4
90.2
N.A.
76.7
83.5
N.A.
83.4
29.7
N.A.
56.6
N.A.
31.6
N.A.
48.2
36.2
P-Site Identity:
100
100
100
86.6
N.A.
0
86.6
N.A.
6.6
0
N.A.
13.3
N.A.
6.6
N.A.
13.3
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
86.6
N.A.
20
0
N.A.
26.6
N.A.
20
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
25
17
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
9
42
9
% C
% Asp:
0
42
17
9
0
9
0
17
0
0
50
17
50
17
42
% D
% Glu:
0
0
0
0
9
0
0
0
9
0
0
42
9
0
17
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
9
0
0
0
0
17
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
9
0
25
9
0
0
0
0
9
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
9
% M
% Asn:
0
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
9
9
0
0
17
0
0
9
% P
% Gln:
9
0
17
0
0
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
9
42
9
0
25
17
0
0
0
0
0
9
0
0
% R
% Ser:
9
9
9
42
75
17
59
50
17
0
9
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
42
9
0
0
0
9
0
0
42
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _