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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASEF
All Species:
22.42
Human Site:
S280
Identified Species:
44.85
UniProt:
Q8IZ41
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ41
NP_689786.2
740
82879
S280
K
K
Q
I
Y
D
L
S
M
E
N
Q
K
V
K
Chimpanzee
Pan troglodytes
XP_520093
989
110305
S529
K
K
Q
I
Y
D
L
S
M
E
N
Q
K
V
K
Rhesus Macaque
Macaca mulatta
XP_001104352
740
82761
S280
K
K
Q
I
Y
D
L
S
M
E
N
Q
K
V
K
Dog
Lupus familis
XP_541269
751
83654
S291
K
K
Q
I
Y
D
L
S
M
E
N
Q
K
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5RI75
627
70734
K176
T
M
E
N
Q
K
L
K
K
E
L
L
E
A
Q
Rat
Rattus norvegicus
XP_001067187
709
79502
T250
K
K
Q
I
Y
D
L
T
T
E
N
Q
K
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511721
743
83385
S280
K
K
K
I
H
D
L
S
M
E
N
Q
K
V
R
Chicken
Gallus gallus
XP_417952
297
32431
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5WW21
663
75839
I212
L
A
D
L
Q
T
T
I
E
R
L
T
K
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP48
388
43018
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22908
656
74591
L205
E
S
E
V
D
Q
Q
L
E
L
T
E
M
K
A
Sea Urchin
Strong. purpuratus
XP_001177439
377
41472
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
95.8
85.7
N.A.
69.5
76
N.A.
72.8
20
N.A.
37.4
N.A.
21
N.A.
28.5
22.9
Protein Similarity:
100
74.5
97.4
90.2
N.A.
76.7
83.5
N.A.
83.4
29.7
N.A.
56.6
N.A.
31.6
N.A.
48.2
36.2
P-Site Identity:
100
100
100
100
N.A.
13.3
80
N.A.
80
0
N.A.
6.6
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
33.3
93.3
N.A.
100
0
N.A.
13.3
N.A.
0
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
50
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
17
0
0
0
0
0
17
59
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
50
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
50
50
9
0
0
9
0
9
9
0
0
0
59
9
42
% K
% Leu:
9
0
0
9
0
0
59
9
0
9
17
9
0
9
0
% L
% Met:
0
9
0
0
0
0
0
0
42
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
50
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
42
0
17
9
9
0
0
0
0
50
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% R
% Ser:
0
9
0
0
0
0
0
42
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
9
9
9
9
0
9
9
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
42
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _