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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DZIP1L
All Species:
13.94
Human Site:
T422
Identified Species:
30.67
UniProt:
Q8IYY4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYY4
NP_775814.1
767
86848
T422
K
V
P
K
A
V
D
T
E
E
D
S
P
E
E
Chimpanzee
Pan troglodytes
XP_516774
767
86902
T422
K
V
P
K
A
V
D
T
E
E
D
S
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001114691
766
86687
A422
E
V
L
K
A
A
D
A
E
E
D
S
P
E
E
Dog
Lupus familis
XP_853725
766
88505
K422
I
W
T
M
S
L
R
K
K
E
G
T
C
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q499E4
774
87575
T421
E
M
P
K
A
V
A
T
E
E
D
S
S
E
E
Rat
Rattus norvegicus
Q5XIA0
776
88007
T421
E
V
P
K
A
V
V
T
E
E
D
S
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512495
891
100705
P504
P
A
P
Q
A
L
D
P
K
S
S
P
T
V
P
Chicken
Gallus gallus
XP_416984
825
93959
E455
E
P
I
E
E
L
S
E
E
E
K
G
N
E
N
Frog
Xenopus laevis
NP_001087009
817
92677
S450
Q
A
P
A
P
L
S
S
H
H
S
E
I
K
P
Zebra Danio
Brachydanio rerio
Q32PN7
756
86366
P419
K
L
S
A
T
P
V
P
V
S
V
V
S
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799867
920
104880
R451
K
K
N
K
D
F
E
R
Q
L
K
G
K
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.4
58.2
N.A.
76.4
76.1
N.A.
29.9
31.3
26.4
36.9
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.4
97.1
73.1
N.A.
85.1
84.2
N.A.
47.8
49.9
47.3
57.8
N.A.
N.A.
N.A.
N.A.
46.5
P-Site Identity:
100
100
73.3
6.6
N.A.
73.3
80
N.A.
20
20
6.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
80
40
N.A.
86.6
86.6
N.A.
40
40
33.3
13.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
19
55
10
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
10
0
37
0
0
0
46
0
0
0
0
% D
% Glu:
37
0
0
10
10
0
10
10
55
64
0
10
0
64
55
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
19
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
37
10
0
55
0
0
0
10
19
0
19
0
10
19
0
% K
% Leu:
0
10
10
0
0
37
0
0
0
10
0
0
0
10
0
% L
% Met:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
19
% N
% Pro:
10
10
55
0
10
10
0
19
0
0
0
10
28
0
19
% P
% Gln:
10
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
19
10
0
19
19
46
28
0
0
% S
% Thr:
0
0
10
0
10
0
0
37
0
0
0
10
10
0
0
% T
% Val:
0
37
0
0
0
37
19
0
10
0
10
10
0
10
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _