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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DZIP1L All Species: 4.55
Human Site: S606 Identified Species: 10
UniProt: Q8IYY4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYY4 NP_775814.1 767 86848 S606 P S S T P P S S G P G M S T P
Chimpanzee Pan troglodytes XP_516774 767 86902 S606 P S S T P P S S G P G M S T P
Rhesus Macaque Macaca mulatta XP_001114691 766 86687 L606 P S S T P P S L G P G M S T P
Dog Lupus familis XP_853725 766 88505 I605 L A Q V P A P I L H Q R A H G
Cat Felis silvestris
Mouse Mus musculus Q499E4 774 87575 G608 T P V S P G S G L S S T P P F
Rat Rattus norvegicus Q5XIA0 776 88007 P608 P S S T P V S P G P G L S T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512495 891 100705 K690 L G D D L P K K S S S V T T P
Chicken Gallus gallus XP_416984 825 93959 D644 E E E A D D D D V K Q L R V S
Frog Xenopus laevis NP_001087009 817 92677 N639 A G P L P S C N T T D S L K L
Zebra Danio Brachydanio rerio Q32PN7 756 86366 L603 P N Q T P K I L A K K N S T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799867 920 104880 L699 Q V R S G P P L A P R S P A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95.4 58.2 N.A. 76.4 76.1 N.A. 29.9 31.3 26.4 36.9 N.A. N.A. N.A. N.A. 26.4
Protein Similarity: 100 99.4 97.1 73.1 N.A. 85.1 84.2 N.A. 47.8 49.9 47.3 57.8 N.A. N.A. N.A. N.A. 46.5
P-Site Identity: 100 100 93.3 6.6 N.A. 13.3 80 N.A. 20 0 6.6 40 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 20 N.A. 20 86.6 N.A. 33.3 6.6 13.3 46.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 0 10 0 0 19 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 10 10 10 10 0 0 10 0 0 0 0 % D
% Glu: 10 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 19 0 0 10 10 0 10 37 0 37 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 10 10 0 19 10 0 0 10 0 % K
% Leu: 19 0 0 10 10 0 0 28 19 0 0 19 10 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 10 0 0 0 10 0 0 0 % N
% Pro: 46 10 10 0 73 46 19 10 0 46 0 0 19 10 55 % P
% Gln: 10 0 19 0 0 0 0 0 0 0 19 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 10 10 10 0 0 % R
% Ser: 0 37 37 19 0 10 46 19 10 19 19 19 46 0 10 % S
% Thr: 10 0 0 46 0 0 0 0 10 10 0 10 10 55 0 % T
% Val: 0 10 10 10 0 10 0 0 10 0 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _