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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DZIP1L
All Species:
9.09
Human Site:
S489
Identified Species:
20
UniProt:
Q8IYY4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYY4
NP_775814.1
767
86848
S489
Q
T
L
R
H
L
E
S
L
L
R
V
Q
R
E
Chimpanzee
Pan troglodytes
XP_516774
767
86902
S489
Q
T
L
R
H
L
E
S
L
L
R
V
Q
R
E
Rhesus Macaque
Macaca mulatta
XP_001114691
766
86687
S489
Q
T
L
R
H
L
E
S
L
L
R
V
Q
R
E
Dog
Lupus familis
XP_853725
766
88505
K488
M
G
I
A
K
N
K
K
R
I
S
T
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q499E4
774
87575
P491
Q
T
V
R
R
L
E
P
L
L
R
T
Q
R
E
Rat
Rattus norvegicus
Q5XIA0
776
88007
P491
Q
T
V
R
R
L
E
P
L
L
R
T
Q
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512495
891
100705
E573
Q
T
L
V
E
K
L
E
S
L
G
I
K
A
G
Chicken
Gallus gallus
XP_416984
825
93959
R527
L
R
A
I
E
S
A
R
E
H
K
L
K
Q
E
Frog
Xenopus laevis
NP_001087009
817
92677
E522
D
H
C
K
K
I
L
E
S
S
K
H
V
R
E
Zebra Danio
Brachydanio rerio
Q32PN7
756
86366
G486
E
N
M
G
L
R
K
G
T
K
G
I
S
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799867
920
104880
R582
Q
S
L
E
N
K
I
R
V
L
K
Q
E
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.4
58.2
N.A.
76.4
76.1
N.A.
29.9
31.3
26.4
36.9
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.4
97.1
73.1
N.A.
85.1
84.2
N.A.
47.8
49.9
47.3
57.8
N.A.
N.A.
N.A.
N.A.
46.5
P-Site Identity:
100
100
100
0
N.A.
73.3
73.3
N.A.
26.6
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
26.6
N.A.
80
80
N.A.
40
33.3
33.3
40
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
10
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
19
0
46
19
10
0
0
0
10
0
64
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
0
0
10
0
0
19
0
0
0
10
% G
% His:
0
10
0
0
28
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
10
10
0
10
10
0
0
10
0
19
0
0
0
% I
% Lys:
0
0
0
10
19
19
19
10
0
10
28
0
28
10
0
% K
% Leu:
10
0
46
0
10
46
19
0
46
64
0
10
0
0
10
% L
% Met:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% P
% Gln:
64
0
0
0
0
0
0
0
0
0
0
10
46
10
19
% Q
% Arg:
0
10
0
46
19
10
0
19
10
0
46
0
0
64
0
% R
% Ser:
0
10
0
0
0
10
0
28
19
10
10
0
10
0
0
% S
% Thr:
0
55
0
0
0
0
0
0
10
0
0
28
0
10
0
% T
% Val:
0
0
19
10
0
0
0
0
10
0
0
28
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _