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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ULK2
All Species:
13.03
Human Site:
S423
Identified Species:
26.06
UniProt:
Q8IYT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYT8
NP_001136082.1
1036
112724
S423
N
L
T
S
T
A
S
S
G
T
N
V
H
G
S
Chimpanzee
Pan troglodytes
XP_511339
1036
112733
S423
N
L
T
S
T
A
S
S
G
T
N
V
H
G
S
Rhesus Macaque
Macaca mulatta
XP_001099375
1049
113890
S436
N
L
T
S
T
A
S
S
G
T
N
V
H
G
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY01
1037
112859
S423
N
L
I
S
T
A
S
S
G
T
N
P
H
G
S
Rat
Rattus norvegicus
B2GUY1
924
103752
K321
V
G
Q
P
L
P
N
K
I
T
V
F
Q
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508434
1038
113312
P423
N
L
T
S
T
G
S
P
G
S
N
P
H
G
S
Chicken
Gallus gallus
Q5ZJH6
468
53047
Frog
Xenopus laevis
Q4V7Q6
468
53109
Zebra Danio
Brachydanio rerio
XP_687208
1027
111406
N417
N
Y
Q
R
I
K
Q
N
L
S
S
S
P
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648601
835
90628
A233
K
S
Y
Y
E
Q
N
A
N
L
A
P
K
I
P
Honey Bee
Apis mellifera
XP_624950
752
82281
C150
S
H
N
C
G
K
A
C
P
Q
P
H
Q
I
T
Nematode Worm
Caenorhab. elegans
Q23023
856
94874
R254
N
L
R
D
L
L
L
R
L
L
K
R
N
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.5
N.A.
N.A.
93.6
22.1
N.A.
86.7
20.8
20.9
75.5
N.A.
35.3
38.5
33.1
N.A.
Protein Similarity:
100
99.6
95.8
N.A.
N.A.
96.1
38.1
N.A.
92.1
30.7
31.9
85.4
N.A.
50.1
51.7
48.7
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
6.6
N.A.
73.3
0
0
6.6
N.A.
0
0
13.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
20
N.A.
80
0
0
33.3
N.A.
13.3
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
34
9
9
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
9
0
0
9
9
0
0
42
0
0
0
0
42
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
9
42
0
0
% H
% Ile:
0
0
9
0
9
0
0
0
9
0
0
0
0
17
0
% I
% Lys:
9
0
0
0
0
17
0
9
0
0
9
0
9
9
9
% K
% Leu:
0
50
0
0
17
9
9
0
17
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
59
0
9
0
0
0
17
9
9
0
42
0
9
0
9
% N
% Pro:
0
0
0
9
0
9
0
9
9
0
9
25
9
0
9
% P
% Gln:
0
0
17
0
0
9
9
0
0
9
0
0
17
0
0
% Q
% Arg:
0
0
9
9
0
0
0
9
0
0
0
9
0
0
0
% R
% Ser:
9
9
0
42
0
0
42
34
0
17
9
9
0
0
42
% S
% Thr:
0
0
34
0
42
0
0
0
0
42
0
0
0
9
17
% T
% Val:
9
0
0
0
0
0
0
0
0
0
9
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _