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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ULK2
All Species:
21.82
Human Site:
S241
Identified Species:
43.64
UniProt:
Q8IYT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYT8
NP_001136082.1
1036
112724
S241
P
S
I
P
R
E
T
S
P
Y
L
A
N
L
L
Chimpanzee
Pan troglodytes
XP_511339
1036
112733
S241
P
S
I
P
R
E
T
S
P
Y
L
A
N
L
L
Rhesus Macaque
Macaca mulatta
XP_001099375
1049
113890
S254
P
S
I
P
R
E
T
S
P
Y
L
A
N
L
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY01
1037
112859
S241
P
S
I
P
R
E
T
S
P
Y
L
A
N
L
L
Rat
Rattus norvegicus
B2GUY1
924
103752
N147
S
N
I
L
L
T
R
N
M
N
I
K
I
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508434
1038
113312
S242
P
S
I
P
R
E
T
S
P
Y
L
T
D
L
L
Chicken
Gallus gallus
Q5ZJH6
468
53047
Frog
Xenopus laevis
Q4V7Q6
468
53109
Zebra Danio
Brachydanio rerio
XP_687208
1027
111406
S241
P
N
I
P
R
E
T
S
P
Q
L
E
D
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648601
835
90628
K60
G
K
E
I
K
I
L
K
E
L
T
E
L
H
H
Honey Bee
Apis mellifera
XP_624950
752
82281
Nematode Worm
Caenorhab. elegans
Q23023
856
94874
P81
L
L
K
C
T
E
T
P
T
H
V
Y
L
V
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.5
N.A.
N.A.
93.6
22.1
N.A.
86.7
20.8
20.9
75.5
N.A.
35.3
38.5
33.1
N.A.
Protein Similarity:
100
99.6
95.8
N.A.
N.A.
96.1
38.1
N.A.
92.1
30.7
31.9
85.4
N.A.
50.1
51.7
48.7
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
6.6
N.A.
86.6
0
0
73.3
N.A.
0
0
13.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
26.6
N.A.
93.3
0
0
86.6
N.A.
6.6
0
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
34
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
9
% D
% Glu:
0
0
9
0
0
59
0
0
9
0
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% H
% Ile:
0
0
59
9
0
9
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
9
9
0
9
0
0
9
0
0
0
9
0
0
0
% K
% Leu:
9
9
0
9
9
0
9
0
0
9
50
0
17
50
50
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
17
0
0
0
0
0
9
0
9
0
0
34
0
0
% N
% Pro:
50
0
0
50
0
0
0
9
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
50
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
42
0
0
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
9
59
0
9
0
9
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
42
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _