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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEFF1
All Species:
39.77
Human Site:
S376
Identified Species:
97.22
UniProt:
Q8IYR6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYR6
NP_003683.2
380
40934
S376
G
H
F
T
S
D
T
S
S
R
M
V
_
_
_
Chimpanzee
Pan troglodytes
XP_001134837
382
41046
S378
G
H
F
T
S
D
T
S
S
R
M
V
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001111631
381
41029
S377
G
H
F
T
S
D
T
S
S
R
M
V
_
_
_
Dog
Lupus familis
XP_532014
454
50994
S450
G
H
F
T
S
D
T
S
S
R
M
V
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFE7
372
40096
S368
G
H
F
T
S
D
T
S
S
R
M
V
_
_
_
Rat
Rattus norvegicus
Q9QYV1
373
40125
S369
G
H
F
T
S
E
T
S
S
R
M
V
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513907
402
44264
S398
G
H
F
T
S
D
T
S
S
R
M
V
_
_
_
Chicken
Gallus gallus
XP_419072
360
39963
S356
G
H
F
T
S
D
T
S
S
R
M
V
_
_
_
Frog
Xenopus laevis
Q91590
370
40312
S366
G
H
F
S
S
D
T
S
S
R
M
V
_
_
_
Zebra Danio
Brachydanio rerio
NP_001020472
364
39443
S360
Q
N
Y
P
S
N
N
S
S
R
M
M
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.4
72.9
N.A.
93.6
93.4
N.A.
75.1
77.8
74.4
51.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.9
75.5
N.A.
95.7
95.7
N.A.
81
84.4
85.2
67.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
91.6
N.A.
100
100
91.6
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
75
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
90
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
90
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
90
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
100
10
0
0
0
% M
% Asn:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% R
% Ser:
0
0
0
10
100
0
0
100
100
0
0
0
0
0
0
% S
% Thr:
0
0
0
80
0
0
90
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
100
100
100
% _