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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLFN12
All Species:
20
Human Site:
Y68
Identified Species:
73.33
UniProt:
Q8IYM2
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYM2
NP_060512.3
578
66972
Y68
A
E
I
E
N
E
D
Y
S
Y
T
K
D
G
I
Chimpanzee
Pan troglodytes
XP_001174240
579
67090
Y68
A
E
I
E
N
E
D
Y
S
Y
T
K
D
G
I
Rhesus Macaque
Macaca mulatta
XP_001114114
580
67337
Y68
A
E
I
E
N
E
D
Y
S
Y
T
K
D
G
I
Dog
Lupus familis
XP_548260
934
105691
Y69
A
E
I
D
D
E
T
Y
S
Y
R
C
H
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBA2
884
100801
Y67
V
E
I
E
N
G
D
Y
N
F
E
R
D
G
V
Rat
Rattus norvegicus
NP_446139
587
66058
Y68
A
R
I
K
N
Q
N
Y
D
F
S
R
D
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084741
897
102950
F79
V
N
I
S
N
E
D
F
S
Y
K
K
H
S
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
89.6
30.4
N.A.
28.7
44.2
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
94.3
44.3
N.A.
42.5
61.5
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
53.3
40
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
80
86.6
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
0
0
0
15
15
0
72
0
15
0
0
0
72
0
0
% D
% Glu:
0
72
0
58
0
72
0
0
0
0
15
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
29
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
0
0
0
0
0
0
0
86
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% H
% Ile:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
43
% I
% Lys:
0
0
0
15
0
0
0
0
0
0
15
58
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
86
0
15
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
0
15
29
0
0
0
% R
% Ser:
0
0
0
15
0
0
0
0
72
0
15
0
0
15
0
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
43
0
0
0
0
% T
% Val:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
72
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _