KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLFN12
All Species:
12.12
Human Site:
S43
Identified Species:
44.44
UniProt:
Q8IYM2
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYM2
NP_060512.3
578
66972
S43
L
R
K
K
Q
N
E
S
V
S
R
A
M
C
A
Chimpanzee
Pan troglodytes
XP_001174240
579
67090
S43
L
R
K
K
Q
N
E
S
V
S
R
A
M
C
A
Rhesus Macaque
Macaca mulatta
XP_001114114
580
67337
S43
L
R
K
K
Q
N
E
S
V
S
R
A
V
C
A
Dog
Lupus familis
XP_548260
934
105691
K44
L
K
R
T
E
N
K
K
I
I
Q
A
T
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBA2
884
100801
I42
H
C
M
K
Q
N
E
I
I
S
Q
A
V
C
A
Rat
Rattus norvegicus
NP_446139
587
66058
T43
R
R
K
R
E
A
K
T
F
Q
Q
A
V
C
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084741
897
102950
N54
Q
K
K
R
E
R
E
N
I
S
K
A
V
C
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
89.6
30.4
N.A.
28.7
44.2
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
94.3
44.3
N.A.
42.5
61.5
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
33.3
N.A.
53.3
26.6
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
66.6
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
0
0
0
100
0
0
86
% A
% Cys:
0
15
0
0
0
0
0
0
0
0
0
0
0
100
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
43
0
72
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
43
15
0
0
0
0
0
% I
% Lys:
0
29
72
58
0
0
29
15
0
0
15
0
0
0
0
% K
% Leu:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
29
0
0
% M
% Asn:
0
0
0
0
0
72
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
58
0
0
0
0
15
43
0
0
0
0
% Q
% Arg:
15
58
15
29
0
15
0
0
0
0
43
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
43
0
72
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
15
0
0
0
0
15
0
15
% T
% Val:
0
0
0
0
0
0
0
0
43
0
0
0
58
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _