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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
13.33
Human Site:
Y523
Identified Species:
24.44
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
Y523
V
D
E
K
R
T
Q
Y
I
K
S
R
R
G
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
Y523
V
D
E
K
R
T
Q
Y
I
K
S
R
R
G
C
Dog
Lupus familis
XP_545909
707
79384
Y479
M
D
K
Q
R
T
R
Y
I
N
S
R
R
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
Y479
M
D
E
Q
R
T
R
Y
L
H
S
R
Q
G
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
V352
P
N
L
L
H
C
K
V
S
N
T
L
I
V
R
Chicken
Gallus gallus
XP_420816
661
74622
N478
V
S
S
E
L
P
E
N
M
M
E
M
A
S
G
Frog
Xenopus laevis
Q4KLT3
668
76749
L478
V
D
N
V
D
S
S
L
V
Q
S
E
K
L
P
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
P163
Y
S
D
G
I
A
Y
P
K
L
S
W
L
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
I344
S
H
E
C
G
Y
E
I
L
Q
D
R
L
K
I
Honey Bee
Apis mellifera
XP_393767
463
53693
K286
K
N
L
E
D
R
I
K
Q
I
L
S
A
K
T
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
R386
G
F
D
V
K
I
D
R
L
A
I
P
S
T
K
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
I448
E
R
S
L
K
D
R
I
T
L
E
V
A
W
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
T338
T
Y
S
T
R
L
E
T
P
T
G
V
Q
E
S
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
100
60
N.A.
53.3
N.A.
N.A.
0
6.6
20
6.6
N.A.
13.3
0
0
0
P-Site Similarity:
100
N.A.
100
86.6
N.A.
86.6
N.A.
N.A.
20
26.6
46.6
13.3
N.A.
33.3
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
0
0
24
0
8
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
16
% C
% Asp:
0
39
16
0
16
8
8
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
31
16
0
0
24
0
0
0
16
8
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
8
0
0
0
0
0
8
0
0
31
8
% G
% His:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
16
% H
% Ile:
0
0
0
0
8
8
8
16
24
8
8
0
8
0
8
% I
% Lys:
8
0
8
16
16
0
8
8
8
16
0
0
8
16
8
% K
% Leu:
0
0
16
16
8
8
0
8
24
16
8
8
16
8
0
% L
% Met:
16
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% M
% Asn:
0
16
8
0
0
0
0
8
0
16
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
8
0
8
8
0
0
8
0
0
8
% P
% Gln:
0
0
0
16
0
0
16
0
8
16
0
0
16
0
0
% Q
% Arg:
0
8
0
0
39
8
24
8
0
0
0
39
24
8
8
% R
% Ser:
8
16
24
0
0
8
8
0
8
0
47
8
8
8
8
% S
% Thr:
8
0
0
8
0
31
0
8
8
8
8
0
0
8
16
% T
% Val:
31
0
0
16
0
0
0
8
8
0
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
8
8
0
0
0
8
8
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _