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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
15.76
Human Site:
Y471
Identified Species:
28.89
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
Y471
K
K
T
Q
Y
R
E
Y
L
D
F
I
K
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
Y471
K
K
T
Q
Y
R
E
Y
L
D
F
I
K
E
V
Dog
Lupus familis
XP_545909
707
79384
Y427
R
K
T
Q
Y
R
E
Y
L
D
F
I
T
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
Y427
R
K
T
Q
Y
R
E
Y
L
D
F
V
L
E
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
S300
L
L
C
R
G
V
L
S
R
R
S
F
Q
R
S
Chicken
Gallus gallus
XP_420816
661
74622
Y426
L
I
G
K
N
R
T
Y
P
P
M
E
R
S
L
Frog
Xenopus laevis
Q4KLT3
668
76749
Q426
S
R
T
Y
P
L
T
Q
E
K
R
I
D
E
Q
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
G111
V
I
V
K
D
I
V
G
H
A
V
T
F
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
V292
E
L
S
P
W
L
P
V
L
A
G
R
L
N
I
Honey Bee
Apis mellifera
XP_393767
463
53693
Q234
R
Y
C
A
S
K
S
Q
Y
S
E
Y
I
D
Y
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
F334
A
A
K
L
N
C
N
F
F
L
I
P
C
C
P
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
R396
D
A
E
C
A
H
S
R
E
L
T
S
S
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
T286
A
F
L
I
E
L
W
T
D
I
Y
G
R
N
F
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
N.A.
N.A.
0
13.3
20
0
N.A.
6.6
0
0
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
N.A.
N.A.
13.3
33.3
26.6
6.6
N.A.
33.3
20
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
0
8
8
0
0
0
0
16
0
0
0
0
0
% A
% Cys:
0
0
16
8
0
8
0
0
0
0
0
0
8
8
0
% C
% Asp:
8
0
0
0
8
0
0
0
8
31
0
0
8
16
0
% D
% Glu:
8
0
8
0
8
0
31
0
16
0
8
8
0
39
0
% E
% Phe:
0
8
0
0
0
0
0
8
8
0
31
8
8
0
8
% F
% Gly:
0
0
8
0
8
0
0
8
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
16
0
8
0
8
0
0
0
8
8
31
8
8
8
% I
% Lys:
16
31
8
16
0
8
0
0
0
8
0
0
16
0
0
% K
% Leu:
16
16
8
8
0
24
8
0
39
16
0
0
16
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
8
0
0
0
0
0
0
16
0
% N
% Pro:
0
0
0
8
8
0
8
0
8
8
0
8
0
0
16
% P
% Gln:
0
0
0
31
0
0
0
16
0
0
0
0
8
0
8
% Q
% Arg:
24
8
0
8
0
39
0
8
8
8
8
8
16
8
0
% R
% Ser:
8
0
8
0
8
0
16
8
0
8
8
8
8
8
16
% S
% Thr:
0
0
39
0
0
0
16
8
0
0
8
8
8
0
0
% T
% Val:
8
0
8
0
0
8
8
8
0
0
8
8
0
0
31
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
31
0
0
39
8
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _