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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
11.52
Human Site:
T507
Identified Species:
21.11
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
T507
C
L
V
G
K
S
R
T
Y
P
S
S
R
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
T507
C
L
I
G
K
S
R
T
Y
P
P
S
R
E
A
Dog
Lupus familis
XP_545909
707
79384
T463
C
L
I
G
K
S
R
T
Y
S
P
A
R
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
T463
C
L
I
G
K
S
R
T
Y
P
P
S
A
E
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
F336
N
G
E
I
S
L
K
F
N
D
S
P
E
H
I
Chicken
Gallus gallus
XP_420816
661
74622
N462
R
E
D
G
F
N
H
N
S
H
S
D
L
C
K
Frog
Xenopus laevis
Q4KLT3
668
76749
L462
D
K
D
D
P
P
P
L
N
C
H
A
K
N
G
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
L147
P
D
E
G
M
F
S
L
H
V
L
R
P
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
D328
T
K
I
S
A
Y
Q
D
F
F
Q
Y
V
T
Q
Honey Bee
Apis mellifera
XP_393767
463
53693
G270
T
K
R
I
C
L
I
G
W
E
R
T
Y
E
N
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
W370
Q
Y
E
S
F
F
E
W
T
V
S
V
A
E
R
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
E432
F
K
P
R
A
V
E
E
R
V
K
N
C
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
D322
G
F
K
G
W
G
F
D
A
R
S
R
K
S
W
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
86.6
66.6
N.A.
73.3
N.A.
N.A.
6.6
13.3
0
13.3
N.A.
0
6.6
13.3
0
P-Site Similarity:
100
N.A.
93.3
80
N.A.
80
N.A.
N.A.
13.3
20
13.3
20
N.A.
20
20
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
0
0
8
0
0
16
16
0
16
% A
% Cys:
31
0
0
0
8
0
0
0
0
8
0
0
8
8
0
% C
% Asp:
8
8
16
8
0
0
0
16
0
8
0
8
0
0
0
% D
% Glu:
0
8
24
0
0
0
16
8
0
8
0
0
8
54
0
% E
% Phe:
8
8
0
0
16
16
8
8
8
8
0
0
0
0
0
% F
% Gly:
8
8
0
54
0
8
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
8
8
8
0
0
8
0
% H
% Ile:
0
0
31
16
0
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
31
8
0
31
0
8
0
0
0
8
0
16
0
8
% K
% Leu:
0
31
0
0
0
16
0
16
0
0
8
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
8
16
0
0
8
0
8
8
% N
% Pro:
8
0
8
0
8
8
8
0
0
24
24
8
8
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
16
% Q
% Arg:
8
0
8
8
0
0
31
0
8
8
8
16
24
0
16
% R
% Ser:
0
0
0
16
8
31
8
0
8
8
39
24
0
16
0
% S
% Thr:
16
0
0
0
0
0
0
31
8
0
0
8
0
8
0
% T
% Val:
0
0
8
0
0
8
0
0
0
24
0
8
8
0
16
% V
% Trp:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
0
8
0
0
31
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _