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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C4orf23 All Species: 12.42
Human Site: S644 Identified Species: 22.78
UniProt: Q8IYL2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYL2 NP_689757 757 84629 S644 K T W N G G E S L S L A E V A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001118752 757 84219 S644 K T W N R G E S L S L A E V A
Dog Lupus familis XP_545909 707 79384 S593 K A W N R G G S L S L T E V A
Cat Felis silvestris
Mouse Mus musculus Q9D2Q2 713 79865 S600 K P W N G G G S L S L A E V A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505248 529 59450 A425 R S P A P S Q A V T P V L S A
Chicken Gallus gallus XP_420816 661 74622 K551 P G E S L S L K E V A E H L N
Frog Xenopus laevis Q4KLT3 668 76749 L551 N T G R S L T L R E V A E H L
Zebra Danio Brachydanio rerio NP_001006086 340 38618 T236 F E D V A I A T Y L L V L W A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHB9 521 59366 K417 I I D G L V F K I F K L I L D
Honey Bee Apis mellifera XP_393767 463 53693 E359 G C T I Y I E E T P K K F W N
Nematode Worm Caenorhab. elegans Q45EK7 563 64854 D459 D F V L N Y S D A V R D G W R
Sea Urchin Strong. purpuratus XP_788093 625 70353 G521 N L K S E C G G L K T L L K N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SE80 515 57926 I411 S D C P F I M I P C C S H D L
Conservation
Percent
Protein Identity: 100 N.A. 92.3 69 N.A. 67.2 N.A. N.A. 32.3 56.6 51.9 25.6 N.A. 29.4 29.8 24.8 35.4
Protein Similarity: 100 N.A. 94.9 77.5 N.A. 77.4 N.A. N.A. 43.5 67.2 65.7 34 N.A. 44.6 41.8 41.2 50.9
P-Site Identity: 100 N.A. 93.3 73.3 N.A. 86.6 N.A. N.A. 6.6 0 20 13.3 N.A. 0 6.6 0 6.6
P-Site Similarity: 100 N.A. 93.3 73.3 N.A. 86.6 N.A. N.A. 46.6 13.3 26.6 20 N.A. 13.3 6.6 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.4
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 32.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 8 8 8 0 8 31 0 0 47 % A
% Cys: 0 8 8 0 0 8 0 0 0 8 8 0 0 0 0 % C
% Asp: 8 8 16 0 0 0 0 8 0 0 0 8 0 8 8 % D
% Glu: 0 8 8 0 8 0 24 8 8 8 0 8 39 0 0 % E
% Phe: 8 8 0 0 8 0 8 0 0 8 0 0 8 0 0 % F
% Gly: 8 8 8 8 16 31 24 8 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 16 8 0 % H
% Ile: 8 8 0 8 0 24 0 8 8 0 0 0 8 0 0 % I
% Lys: 31 0 8 0 0 0 0 16 0 8 16 8 0 8 0 % K
% Leu: 0 8 0 8 16 8 8 8 39 8 39 16 24 16 16 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 31 8 0 0 0 0 0 0 0 0 0 24 % N
% Pro: 8 8 8 8 8 0 0 0 8 8 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 8 16 0 0 0 8 0 8 0 0 0 8 % R
% Ser: 8 8 0 16 8 16 8 31 0 31 0 8 0 8 0 % S
% Thr: 0 24 8 0 0 0 8 8 8 8 8 8 0 0 0 % T
% Val: 0 0 8 8 0 8 0 0 8 16 8 16 0 31 0 % V
% Trp: 0 0 31 0 0 0 0 0 0 0 0 0 0 24 0 % W
% Tyr: 0 0 0 0 8 8 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _