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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
12.73
Human Site:
S533
Identified Species:
23.33
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
S533
S
R
R
G
C
P
V
S
P
P
G
W
E
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
S533
S
R
R
G
C
P
V
S
P
P
G
R
E
L
C
Dog
Lupus familis
XP_545909
707
79384
S489
S
R
R
G
H
L
A
S
P
P
G
E
T
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
S489
S
R
Q
G
H
P
Q
S
R
P
G
G
A
H
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
Y362
T
L
I
V
R
K
N
Y
F
T
V
T
W
I
R
Chicken
Gallus gallus
XP_420816
661
74622
M488
E
M
A
S
G
I
W
M
P
G
F
Q
P
R
E
Frog
Xenopus laevis
Q4KLT3
668
76749
W488
S
E
K
L
P
G
S
W
M
P
G
F
Q
P
R
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
L173
S
W
L
R
T
E
L
L
P
K
L
S
R
W
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
T354
D
R
L
K
I
P
S
T
K
R
L
A
L
L
G
Honey Bee
Apis mellifera
XP_393767
463
53693
T296
L
S
A
K
T
T
L
T
K
Q
K
Y
E
S
N
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
C396
I
P
S
T
K
R
L
C
I
I
G
R
V
P
E
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
E458
E
V
A
W
A
I
L
E
D
G
G
V
R
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
Q348
G
V
Q
E
S
L
Q
Q
L
V
L
L
P
P
P
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
86.6
53.3
N.A.
46.6
N.A.
N.A.
0
6.6
20
20
N.A.
20
6.6
6.6
13.3
P-Site Similarity:
100
N.A.
86.6
60
N.A.
60
N.A.
N.A.
13.3
6.6
40
26.6
N.A.
26.6
33.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
8
0
8
0
0
0
0
8
8
0
16
% A
% Cys:
0
0
0
0
16
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
16
8
0
8
0
8
0
8
0
0
0
8
24
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% F
% Gly:
8
0
0
31
8
8
0
0
0
16
54
8
0
0
8
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
8
0
8
16
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
8
16
8
8
0
0
16
8
8
0
0
0
0
% K
% Leu:
8
8
16
8
0
16
31
8
8
0
24
8
8
24
0
% L
% Met:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
0
8
31
0
0
39
39
0
0
16
31
8
% P
% Gln:
0
0
16
0
0
0
16
8
0
8
0
8
8
0
0
% Q
% Arg:
0
39
24
8
8
8
0
0
8
8
0
16
16
16
16
% R
% Ser:
47
8
8
8
8
0
16
31
0
0
0
8
0
8
24
% S
% Thr:
8
0
0
8
16
8
0
16
0
8
0
8
8
0
0
% T
% Val:
0
16
0
8
0
0
16
0
0
8
8
8
8
0
0
% V
% Trp:
0
8
0
8
0
0
8
8
0
0
0
8
8
8
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _