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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
4.55
Human Site:
S375
Identified Species:
8.33
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
S375
L
L
V
H
I
L
S
S
E
G
H
P
G
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
S375
L
L
V
H
I
L
N
S
E
G
H
P
G
R
G
Dog
Lupus familis
XP_545909
707
79384
G338
T
E
G
H
P
G
R
G
I
D
V
R
R
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
G338
N
E
G
H
P
G
R
G
I
D
I
R
R
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
G211
R
K
I
W
A
T
Y
G
P
Q
T
H
L
E
E
Chicken
Gallus gallus
XP_420816
661
74622
L337
L
F
P
D
T
D
W
L
I
G
N
H
S
D
E
Frog
Xenopus laevis
Q4KLT3
668
76749
H337
T
D
W
L
I
G
N
H
S
D
E
L
T
P
W
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
H22
D
V
W
I
N
K
P
H
V
V
N
K
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
V203
A
I
A
A
Y
L
I
V
L
W
S
Q
T
Q
S
Honey Bee
Apis mellifera
XP_393767
463
53693
H145
I
L
F
S
E
G
H
H
G
L
G
I
D
L
R
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
K245
D
L
L
P
K
P
N
K
F
V
D
I
G
C
G
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
P307
E
E
D
K
M
R
I
P
S
T
K
K
I
C
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
E197
S
V
S
Y
L
Y
F
E
G
G
E
R
P
E
K
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
93.3
13.3
N.A.
13.3
N.A.
N.A.
0
13.3
6.6
0
N.A.
6.6
6.6
20
0
P-Site Similarity:
100
N.A.
100
13.3
N.A.
13.3
N.A.
N.A.
6.6
20
13.3
13.3
N.A.
20
13.3
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% C
% Asp:
16
8
8
8
0
8
0
0
0
24
8
0
8
8
0
% D
% Glu:
8
24
0
0
8
0
0
8
16
0
16
0
0
16
16
% E
% Phe:
0
8
8
0
0
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
16
0
0
31
0
24
16
31
8
0
24
0
24
% G
% His:
0
0
0
31
0
0
8
24
0
0
16
16
0
0
8
% H
% Ile:
8
8
8
8
24
0
16
0
24
0
8
16
8
0
0
% I
% Lys:
0
8
0
8
8
8
0
8
0
0
8
16
0
0
24
% K
% Leu:
24
31
8
8
8
24
0
8
8
8
0
8
8
16
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
24
0
0
0
16
0
0
0
0
% N
% Pro:
0
0
8
8
16
8
8
8
8
0
0
16
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% Q
% Arg:
8
0
0
0
0
8
16
0
0
0
0
24
24
31
8
% R
% Ser:
8
0
8
8
0
0
8
16
16
0
8
0
8
0
16
% S
% Thr:
16
0
0
0
8
8
0
0
0
8
8
0
16
0
0
% T
% Val:
0
16
16
0
0
0
0
8
8
16
8
0
0
0
0
% V
% Trp:
0
0
16
8
0
0
8
0
0
8
0
0
0
0
8
% W
% Tyr:
0
0
0
8
8
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _