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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
6.97
Human Site:
S288
Identified Species:
12.78
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
S288
W
S
V
E
N
K
K
S
D
F
K
S
T
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
S288
W
S
V
E
N
K
K
S
D
F
K
S
T
L
S
Dog
Lupus familis
XP_545909
707
79384
S251
S
E
F
K
S
T
L
S
L
I
S
I
I
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
S251
S
E
F
K
S
T
L
S
L
V
S
I
L
R
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
L125
Y
T
R
L
Y
R
E
L
K
D
R
Y
R
D
A
Chicken
Gallus gallus
XP_420816
661
74622
D251
P
E
K
F
V
Y
E
D
V
A
I
A
T
Y
L
Frog
Xenopus laevis
Q4KLT3
668
76749
A251
V
Y
E
D
V
A
I
A
T
Y
L
L
I
I
W
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
K117
G
L
L
G
G
E
F
K
L
K
S
K
S
N
T
Honey Bee
Apis mellifera
XP_393767
463
53693
L59
T
P
I
S
L
S
S
L
N
F
V
S
T
E
K
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
M159
S
Q
E
H
F
E
F
M
K
K
Q
A
F
K
Q
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
S221
E
E
S
T
I
I
A
S
M
E
T
S
F
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
H111
S
F
D
G
F
G
L
H
R
R
L
I
R
R
L
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
100
6.6
N.A.
6.6
N.A.
N.A.
0
6.6
0
0
N.A.
0
20
0
13.3
P-Site Similarity:
100
N.A.
100
20
N.A.
20
N.A.
N.A.
40
20
26.6
0
N.A.
26.6
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
0
8
0
16
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
8
16
8
0
0
0
8
8
% D
% Glu:
8
31
16
16
0
16
16
0
0
8
0
0
0
8
0
% E
% Phe:
0
8
16
8
16
0
16
0
0
24
0
0
16
0
0
% F
% Gly:
8
0
0
16
8
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
8
0
0
8
8
24
16
8
0
% I
% Lys:
0
0
8
16
0
16
16
8
16
16
16
8
0
24
8
% K
% Leu:
0
8
8
8
8
0
24
16
24
0
16
8
8
16
16
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
0
8
0
0
8
0
0
8
8
8
0
16
16
0
% R
% Ser:
31
16
8
8
16
8
8
39
0
0
24
31
8
0
16
% S
% Thr:
8
8
0
8
0
16
0
0
8
0
8
0
31
0
8
% T
% Val:
8
0
16
0
16
0
0
0
8
8
8
0
0
0
0
% V
% Trp:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
8
0
0
8
8
0
0
0
8
0
8
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _