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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC8
All Species:
26.97
Human Site:
Y227
Identified Species:
49.44
UniProt:
Q8IYI6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYI6
NP_787072.2
725
81799
Y227
Q
R
R
G
M
Y
R
Y
N
A
L
Y
S
L
D
Chimpanzee
Pan troglodytes
XP_513085
725
81753
Y227
Q
R
R
G
M
Y
R
Y
N
A
L
Y
S
L
D
Rhesus Macaque
Macaca mulatta
XP_001104940
725
81803
Y227
Q
R
R
G
M
Y
R
Y
N
A
L
Y
S
L
D
Dog
Lupus familis
XP_546091
727
81898
Y229
Q
R
R
G
M
Y
R
Y
N
A
L
Y
P
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF7
716
81017
Y218
Q
R
R
G
M
Y
R
Y
N
A
L
Y
P
L
D
Rat
Rattus norvegicus
O54924
716
81025
Y218
Q
R
R
G
M
Y
R
Y
N
A
L
Y
P
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521396
411
45838
Chicken
Gallus gallus
Q5ZJ43
708
80411
Y213
N
R
R
G
A
Y
R
Y
D
A
L
Y
P
L
E
Frog
Xenopus laevis
Q5U247
685
78756
V208
N
L
D
D
L
A
V
V
N
V
K
E
N
P
P
Zebra Danio
Brachydanio rerio
NP_001103945
684
78737
V206
Y
D
L
E
S
F
A
V
V
N
V
K
D
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651454
671
76512
Y215
T
P
D
G
S
K
I
Y
Q
S
I
T
A
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021702
686
77793
P222
V
L
K
L
L
I
F
P
E
S
R
C
Y
L
C
Sea Urchin
Strong. purpuratus
XP_794695
756
86307
Q274
K
N
H
P
D
Y
K
Q
P
R
Q
S
S
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
93.2
92.1
N.A.
43.1
82.7
73.9
73.9
N.A.
27.3
N.A.
25.3
44.4
Protein Similarity:
100
100
99.7
98.4
N.A.
95.1
94.3
N.A.
48.8
88.5
84
84.5
N.A.
48.1
N.A.
45.9
64.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
66.6
6.6
0
N.A.
13.3
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
80
20
13.3
N.A.
33.3
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
0
0
54
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
8
16
8
8
0
0
0
8
0
0
0
8
0
47
% D
% Glu:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
8
0
0
0
0
% I
% Lys:
8
0
8
0
0
8
8
0
0
0
8
8
0
8
8
% K
% Leu:
0
16
8
8
16
0
0
0
0
0
54
0
0
62
0
% L
% Met:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
0
0
0
0
0
0
54
8
0
0
8
8
0
% N
% Pro:
0
8
0
8
0
0
0
8
8
0
0
0
31
8
16
% P
% Gln:
47
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% Q
% Arg:
0
54
54
0
0
0
54
0
0
8
8
0
0
0
0
% R
% Ser:
0
0
0
0
16
0
0
0
0
16
0
8
31
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
8
0
0
0
0
0
8
16
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
62
0
62
0
0
0
54
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _