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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC8
All Species:
24.55
Human Site:
S372
Identified Species:
45
UniProt:
Q8IYI6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYI6
NP_787072.2
725
81799
S372
H
Y
L
E
D
K
P
S
P
P
P
V
K
E
L
Chimpanzee
Pan troglodytes
XP_513085
725
81753
S372
H
Y
L
E
D
K
P
S
P
P
P
V
K
E
L
Rhesus Macaque
Macaca mulatta
XP_001104940
725
81803
S372
H
Y
L
E
D
K
P
S
P
P
P
V
K
E
L
Dog
Lupus familis
XP_546091
727
81898
S374
H
Y
L
E
D
K
P
S
P
P
P
V
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF7
716
81017
S363
H
Y
L
E
D
K
P
S
P
P
P
V
K
E
L
Rat
Rattus norvegicus
O54924
716
81025
S363
H
Y
L
E
D
K
P
S
P
P
S
V
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521396
411
45838
C89
L
L
E
K
V
E
G
C
R
P
L
L
D
T
P
Chicken
Gallus gallus
Q5ZJ43
708
80411
V356
E
Y
L
A
D
K
P
V
S
Q
P
V
K
E
L
Frog
Xenopus laevis
Q5U247
685
78756
L333
S
Y
L
E
D
K
P
L
T
H
P
V
K
E
L
Zebra Danio
Brachydanio rerio
NP_001103945
684
78737
V332
E
Y
L
K
D
Q
P
V
S
P
R
V
K
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651454
671
76512
A329
K
K
L
P
L
A
D
A
I
E
T
K
V
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021702
686
77793
T338
H
E
W
K
Q
C
P
T
K
D
A
V
I
D
I
Sea Urchin
Strong. purpuratus
XP_794695
756
86307
V385
E
Y
L
E
Q
V
P
V
G
P
S
L
K
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
93.2
92.1
N.A.
43.1
82.7
73.9
73.9
N.A.
27.3
N.A.
25.3
44.4
Protein Similarity:
100
100
99.7
98.4
N.A.
95.1
94.3
N.A.
48.8
88.5
84
84.5
N.A.
48.1
N.A.
45.9
64.1
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
6.6
66.6
73.3
60
N.A.
6.6
N.A.
20
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
26.6
66.6
73.3
73.3
N.A.
20
N.A.
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
70
0
8
0
0
8
0
0
8
8
0
% D
% Glu:
24
8
8
62
0
8
0
0
0
8
0
0
0
77
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% I
% Lys:
8
8
0
24
0
62
0
0
8
0
0
8
77
8
0
% K
% Leu:
8
8
85
0
8
0
0
8
0
0
8
16
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
85
0
47
70
54
0
0
0
8
% P
% Gln:
0
0
0
0
16
8
0
0
0
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
47
16
0
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
8
0
0
8
0
% T
% Val:
0
0
0
0
8
8
0
24
0
0
0
77
8
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _