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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC8
All Species:
37.27
Human Site:
S259
Identified Species:
68.33
UniProt:
Q8IYI6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYI6
NP_787072.2
725
81799
S259
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Chimpanzee
Pan troglodytes
XP_513085
725
81753
S259
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Rhesus Macaque
Macaca mulatta
XP_001104940
725
81803
S259
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Dog
Lupus familis
XP_546091
727
81898
S261
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF7
716
81017
S250
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Rat
Rattus norvegicus
O54924
716
81025
S250
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521396
411
45838
S14
I
E
T
A
R
E
I
S
Y
L
E
S
A
M
Y
Chicken
Gallus gallus
Q5ZJ43
708
80411
S245
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Frog
Xenopus laevis
Q5U247
685
78756
S228
K
I
L
M
F
P
E
S
R
I
F
Q
A
E
N
Zebra Danio
Brachydanio rerio
NP_001103945
684
78737
S227
K
I
L
M
F
P
D
S
R
I
F
K
A
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651454
671
76512
P242
R
F
D
Q
Q
K
K
P
K
K
G
Q
A
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021702
686
77793
L242
R
T
L
W
F
D
E
L
E
Q
A
K
R
E
I
Sea Urchin
Strong. purpuratus
XP_794695
756
86307
L296
R
N
V
G
M
D
E
L
G
L
G
D
I
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
93.2
92.1
N.A.
43.1
82.7
73.9
73.9
N.A.
27.3
N.A.
25.3
44.4
Protein Similarity:
100
100
99.7
98.4
N.A.
95.1
94.3
N.A.
48.8
88.5
84
84.5
N.A.
48.1
N.A.
45.9
64.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
93.3
80
N.A.
13.3
N.A.
26.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
33.3
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
0
85
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
16
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
0
0
0
8
77
0
8
0
8
0
0
77
0
% E
% Phe:
0
8
0
0
77
0
0
0
0
0
70
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
8
0
16
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
0
0
0
8
0
0
70
0
0
8
0
8
% I
% Lys:
70
0
0
0
0
8
8
0
8
8
0
16
0
0
0
% K
% Leu:
0
54
77
0
0
0
0
16
0
16
0
0
0
0
0
% L
% Met:
0
0
0
70
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
77
% N
% Pro:
0
0
0
0
0
70
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
8
0
0
0
0
8
0
70
0
0
8
% Q
% Arg:
24
0
0
0
8
0
0
0
70
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
77
0
0
0
8
0
0
0
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _